000079770 001__ 79770
000079770 005__ 20200716101424.0
000079770 0247_ $$2doi$$a10.1186/s12931-019-1084-0
000079770 0248_ $$2sideral$$a112655
000079770 037__ $$aART-2019-112655
000079770 041__ $$aeng
000079770 100__ $$aFernández-Fabrellas, Estrella
000079770 245__ $$aDemographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain: the SEPAR National Registry
000079770 260__ $$c2019
000079770 5060_ $$aAccess copy available to the general public$$fUnrestricted
000079770 5203_ $$aBackgroundLittle is known on the characteristics of patients diagnosed with idiopathic pulmonary fibrosis (IPF) in Spain. We aimed to characterize the demographic and clinical profile of IPF patients included in the IPF National Registry of the Spanish Respiratory Society (SEPAR).MethodsThis is a prospective, observational, multicentre and nationwide study that involved 608 IPF patients included in the SEPAR IPF Registry up to June 27th, 2017, and who received any treatment for their disease. IPF patients were predominantly males, ex-smokers, and aged in their 70s, similar to other registries.ResultsUpon inclusion, meanSD predicted forced vital capacity was 77.6%+/- 19.4, diffusing capacity for carbon monoxide was 48.5%+/- 17.7, and the 6-min walk distance was 423.5m +/- 110.4. The diagnosis was mainly established on results from the high-resolution computed tomography in the proper clinical context (55.0% of patients), while 21.2% of patients required invasive procedures (surgical lung biopsy) for definitive diagnosis. Anti-fibrotic treatment was prescribed in 69.4% of cases, 51.5% pirfenidone and 17.9% nintedanib, overall with a good safety profile.Conclusions The SEPAR IPF Registry should help to further characterize current characteristics and future trends of IPF patients in Spain and compare/pool them with other registries and cohorts.
000079770 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000079770 590__ $$a3.924$$b2019
000079770 592__ $$a1.436$$b2019
000079770 591__ $$aRESPIRATORY SYSTEM$$b18 / 64 = 0.281$$c2019$$dQ2$$eT1
000079770 593__ $$aPulmonary and Respiratory Medicine$$c2019$$dQ1
000079770 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000079770 700__ $$aMolina-Molina, María
000079770 700__ $$aSoriano, Joan B.
000079770 700__ $$aPortal, José Antonio Rodríguez
000079770 700__ $$aAncochea, Julio
000079770 700__ $$aValenzuela, Claudia
000079770 700__ $$aXaubet, Antoni
000079770 700__ $$aAburto Barrenetxea, M.
000079770 700__ $$aAlfageme Michavila, I.
000079770 700__ $$aBollo de Miguel, E.
000079770 700__ $$aCano, E.
000079770 700__ $$aCasanova Espinosa, A.
000079770 700__ $$aCastillo Villegas, D.
000079770 700__ $$aFiguerola Mendal, J. A.$$uUniversidad de Zaragoza
000079770 700__ $$aGarcía Sevila, R.
000079770 700__ $$aGaudó Navarro, J. I.
000079770 700__ $$aGómez Carrera, L.
000079770 700__ $$aGonzález, J. M.
000079770 700__ $$aHerrera Lara, S.
000079770 700__ $$aLaporta Hernández, R.
000079770 700__ $$aMarín González, M.
000079770 700__ $$aNieto Barbero, M. A.
000079770 700__ $$aPortillo, K.
000079770 700__ $$aRomero, A. D.
000079770 700__ $$aSánchez Simón-Talero, R.
000079770 700__ $$aSancho Chust, J. N.
000079770 700__ $$aSellarés Torres, J.
000079770 700__ $$aSoler Sempere, M. J.
000079770 700__ $$aSauleda Roig, J.
000079770 700__ $$aTomás López, L.
000079770 700__ $$aVillanueva Montes, M.
000079770 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000079770 773__ $$g20 (2019), 127 [10 pp]$$pRespir. res.$$tRespiratory research$$x1465-9921
000079770 8564_ $$s1145003$$uhttps://zaguan.unizar.es/record/79770/files/texto_completo.pdf$$yVersión publicada
000079770 8564_ $$s107433$$uhttps://zaguan.unizar.es/record/79770/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000079770 909CO $$ooai:zaguan.unizar.es:79770$$particulos$$pdriver
000079770 951__ $$a2020-07-16-08:43:32
000079770 980__ $$aARTICLE