000079790 001__ 79790 000079790 005__ 20200716101522.0 000079790 0247_ $$2doi$$a10.1155/2019/7645352 000079790 0248_ $$2sideral$$a112599 000079790 037__ $$aART-2019-112599 000079790 041__ $$aeng 000079790 100__ $$0(orcid)0000-0002-9325-9964$$adel Buey, María A.$$uUniversidad de Zaragoza 000079790 245__ $$aAn Update on Corneal Biomechanics and Architecture in Diabetes 000079790 260__ $$c2019 000079790 5060_ $$aAccess copy available to the general public$$fUnrestricted 000079790 5203_ $$aIn the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the main and most widely recognized ocular effect of diabetes is on the retina, the structure of the cornea (the outermost and transparent tissue of the eye) can also be affected by the poor glycemic control characterizing diabetes. e different corneal structures (epithelium, stroma, and endothelium) are affected by specific complications of diabetes. e development of new noninvasive diagnostic technologies has provided a better understanding of corneal tissue modifications. e objective of this review is to describe the advances in the knowledge of the corneal alterations that diabetes can induce 000079790 536__ $$9info:eu-repo/grantAgreement/ES/DGA/T88$$9info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84047-R 000079790 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000079790 590__ $$a1.447$$b2019 000079790 591__ $$aOPHTHALMOLOGY$$b41 / 60 = 0.683$$c2019$$dQ3$$eT3 000079790 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b116 / 138 = 0.841$$c2019$$dQ4$$eT3 000079790 592__ $$a0.828$$b2019 000079790 593__ $$aOphthalmology$$c2019$$dQ2 000079790 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000079790 700__ $$aCasas, Paula 000079790 700__ $$aCaramello, Constanza 000079790 700__ $$aLópez, Nuria 000079790 700__ $$0(orcid)0000-0002-3472-5216$$ade la Rica, Marisa$$uUniversidad de Zaragoza 000079790 700__ $$0(orcid)0000-0002-5676-4179$$aSubirón, Ana B.$$uUniversidad de Zaragoza 000079790 700__ $$0(orcid)0000-0002-2959-0628$$aLanchares, Elena$$uUniversidad de Zaragoza 000079790 700__ $$aHuerva, Valentín 000079790 700__ $$aGrzybowski, Andrzej 000079790 700__ $$0(orcid)0000-0001-9876-5850$$aAscaso, Francisco J.$$uUniversidad de Zaragoza 000079790 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería 000079790 7102_ $$11004$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Oftalmología 000079790 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est. 000079790 773__ $$g2019 (2019), 7645352 [20 pp]$$pJ. Ophthalmol.$$tJournal of Ophthalmology$$x2090-004X 000079790 8564_ $$s581137$$uhttps://zaguan.unizar.es/record/79790/files/texto_completo.pdf$$yVersión publicada 000079790 8564_ $$s91150$$uhttps://zaguan.unizar.es/record/79790/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000079790 909CO $$ooai:zaguan.unizar.es:79790$$particulos$$pdriver 000079790 951__ $$a2020-07-16-09:27:49 000079790 980__ $$aARTICLE