000084172 001__ 84172 000084172 005__ 20200716101515.0 000084172 0247_ $$2doi$$a10.1146/annurev-ento-011118-111932 000084172 0248_ $$2sideral$$a110397 000084172 037__ $$aART-2019-110397 000084172 041__ $$aeng 000084172 100__ $$aGray, J.S. 000084172 245__ $$aVectors of babesiosis 000084172 260__ $$c2019 000084172 5060_ $$aAccess copy available to the general public$$fUnrestricted 000084172 5203_ $$aBabesiosis, caused by piroplasmid protozoans in the genus Babesia, is arguably the most important vector-borne disease of livestock and companion animals and is growing in importance as a zoonosis. Ixodid ticks were identified as vectors more than a hundred years ago, but the particular tick species transmitting some significant pathogens are still unknown. Moreover, it is only recently that the complexity of the pathogen-tick relationship has been revealed as a result of studies enabled by gene expression and RNA interference methodology. In this article, we provide details of demonstrated and incriminated vectors, maps of the current knowledge of vector distribution, a summary of established features of the pathogen life cycle in the vector, and an outline of molecular research on pathogen-tick relationships. The article concludes with a discussion of vector ecology and disease epidemiology in a global-change context and with suggestions for future research. 000084172 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000084172 590__ $$a13.796$$b2019 000084172 591__ $$aENTOMOLOGY$$b1 / 101 = 0.01$$c2019$$dQ1$$eT1 000084172 592__ $$a5.869$$b2019 000084172 593__ $$aInsect Science$$c2019$$dQ1 000084172 593__ $$aEcology, Evolution, Behavior and Systematics$$c2019$$dQ1 000084172 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion 000084172 700__ $$0(orcid)0000-0001-7483-046X$$aEstrada-Peña, A.$$uUniversidad de Zaragoza 000084172 700__ $$aZintl, A. 000084172 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000084172 773__ $$g64 (2019), 149-165$$pAnnu. rev. entomol.$$tAnnual Review of Entomology$$x0066-4170 000084172 8564_ $$s615994$$uhttps://zaguan.unizar.es/record/84172/files/texto_completo.pdf$$yPostprint 000084172 8564_ $$s48627$$uhttps://zaguan.unizar.es/record/84172/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000084172 909CO $$ooai:zaguan.unizar.es:84172$$particulos$$pdriver 000084172 951__ $$a2020-07-16-09:22:00 000084172 980__ $$aARTICLE