Resumen: In previous research a novel methodology to assess structural vulnerability was proposed and applied in IEEE test system and high voltage transmission networks of 94 buses, by using graph theory to investigate various risk scenarios that can trigger cascading failures. In this paper we validate the application of this methodology in larger networks by applying a case study on the transmission network 230 and 400 kV of Mexico. The events of cascading failures are simulated through two elimination strategies: by deliberate attacks on critical nodes or by random errors. Iterations are performed by running successive N-1 contingencies on a network that is constantly changing its structure with the elimination of each node. The power flows are not necessary and only the calculation of the graph statistical parameter geodesic vulnerability is required. This reduces the computation time and leads to a comparative analysis of structural vulnerability. Idioma: Inglés DOI: 10.1109/TLA.2018.8327409 Año: 2018 Publicado en: IEEE LATIN AMERICA TRANSACTIONS 16, 2 (2018), 527-535 [9 pp.] ISSN: 1548-0992 Factor impacto JCR: 0.804 (2018) Categ. JCR: ENGINEERING, ELECTRICAL & ELECTRONIC rank: 227 / 265 = 0.857 (2018) - Q4 - T3 Categ. JCR: COMPUTER SCIENCE, INFORMATION SYSTEMS rank: 137 / 155 = 0.884 (2018) - Q4 - T3 Factor impacto SCIMAGO: 0.337 - Electrical and Electronic Engineering (Q2) - Computer Science (miscellaneous) (Q2)