000084321 001__ 84321
000084321 005__ 20201105083209.0
000084321 0247_ $$2doi$$a10.1016/j.neubiorev.2018.09.025
000084321 0248_ $$2sideral$$a109568
000084321 037__ $$aART-2018-109568
000084321 041__ $$aeng
000084321 100__ $$aGilmour, G.
000084321 245__ $$aRelating constructs of attention and working memory to social withdrawal in Alzheimer's disease and schizophrenia: issues regarding paradigm selection
000084321 260__ $$c2018
000084321 5060_ $$aAccess copy available to the general public$$fUnrestricted
000084321 5203_ $$aCentral nervous system diseases are not currently diagnosed based on knowledge of biological mechanisms underlying their symptoms. Greater understanding may be offered through an agnostic approach to traditional disease categories, where learning more about shared biological mechanisms across conditions could potentially reclassify sub-groups of patients to allow realisation of more effective treatments. This review represents the output of the collaborative group “PRISM”, tasked with considering assay choices for assessment of attention and working memory in a transdiagnostic cohort of Alzheimer''s disease and schizophrenia patients exhibiting symptomatic spectra of social withdrawal. A multidimensional analysis of this nature has not been previously attempted. Nominated assays (continuous performance test III, attention network test, digit symbol substitution, N-back, complex span, spatial navigation in a virtual environment) reflected a necessary compromise between the need for broad assessment of the neuropsychological constructs in question with several pragmatic criteria: patient burden, compatibility with neurophysiologic measures and availability of preclinical homologues.
000084321 536__ $$9info:eu-repo/grantAgreement/EC/H2020/115916/EU/Psychiatric Ratings using Intermediate Stratified Markers/PRISM$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 115916-PRISM
000084321 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000084321 590__ $$a8.002$$b2018
000084321 591__ $$aNEUROSCIENCES$$b18 / 266 = 0.068$$c2018$$dQ1$$eT1
000084321 591__ $$aBEHAVIORAL SCIENCES$$b3 / 53 = 0.057$$c2018$$dQ1$$eT1
000084321 592__ $$a3.734$$b2018
000084321 593__ $$aBehavioral Neuroscience$$c2018$$dQ1
000084321 593__ $$aNeuropsychology and Physiological Psychology$$c2018$$dQ1
000084321 593__ $$aCognitive Neuroscience$$c2018$$dQ1
000084321 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000084321 700__ $$aPorcelli, S.
000084321 700__ $$aBertaina-Anglade, V.
000084321 700__ $$aArce, E.
000084321 700__ $$aDukart, J.
000084321 700__ $$aHayen, A.
000084321 700__ $$0(orcid)0000-0003-3025-8048$$aLobo, A.$$uUniversidad de Zaragoza
000084321 700__ $$0(orcid)0000-0002-3360-7015$$aLopez-Anton, R.$$uUniversidad de Zaragoza
000084321 700__ $$aMerlo Pich, E.
000084321 700__ $$aPemberton, D.J.
000084321 700__ $$aHavenith, M.N.
000084321 700__ $$aGlennon, J.C.
000084321 700__ $$aHarel, B.T.
000084321 700__ $$aDawson, G.
000084321 700__ $$aMarston, H.
000084321 700__ $$aKozak, R.
000084321 700__ $$aSerretti, A.
000084321 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica
000084321 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000084321 773__ $$g97 (2018), 47-69$$pNeurosci. biobehav. rev.$$tNEUROSCIENCE AND BIOBEHAVIORAL REVIEWS$$x0149-7634
000084321 8564_ $$s870551$$uhttps://zaguan.unizar.es/record/84321/files/texto_completo.pdf$$yPostprint
000084321 8564_ $$s59712$$uhttps://zaguan.unizar.es/record/84321/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000084321 909CO $$ooai:zaguan.unizar.es:84321$$particulos$$pdriver
000084321 951__ $$a2020-11-05-08:20:34
000084321 980__ $$aARTICLE