84326 20200716101455.0 doi 10.1016/j.foodchem.2018.10.107 sideral 108888 ART-2019-108888 eng Tighrine, A. Simultaneous extraction and analysis of preservatives and artificial sweeteners in juices by salting out liquid-liquid extraction method prior to ultra-high performance liquid chromatography 2019 Access copy available to the general public Unrestricted A novel and fast salting out liquid-liquid extraction method was developed for simultaneous determination of food additives with different polarities in juices. Chromatographic separation was achieved in less than 6 min using Acquity UPLC BEH C 18 (100 mm × 2.1 mm d.i. × 1.7 µm) column with ammonium acetate with 0.01% of trifluoroacetic acid as eluent A and acetonitrile as eluent B at a flow rate of 0.2 mL min-1. The main factors affecting the extraction efficiency were optimized. The method was validated applying accuracy profile based on total error. The extraction recoveries ranged from 84.97 to 122%. Relative standard deviation ranged from 1.24 to 7.99% for intraday assay and from 1.69 to 9.16% for intermediate precision. The limits of detection for five food additives were from 0.3 to 1.42 µg mL-1. The method was successfully applied to 47 samples of juices from nine brands. info:eu-repo/grantAgreement/ES/DGA/T53-17R info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 6.306 2019 CHEMISTRY, APPLIED 5 / 71 = 0.07 2019 Q1 T1 NUTRITION & DIETETICS 10 / 89 = 0.112 2019 Q1 T1 FOOD SCIENCE & TECHNOLOGY 6 / 139 = 0.043 2019 Q1 T1 1.775 2019 Analytical Chemistry 2019 Q1 Medicine (miscellaneous) 2019 Q1 Food Science 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Amir, Y. (orcid)0000-0002-3703-7902 Alfaro, P. Universidad de Zaragoza Mamou, M. (orcid)0000-0003-2685-5739 Nerín, C. Universidad de Zaragoza 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 2009 X Universidad de Zaragoza Dpto. Química Analítica Proy. investigación HVA 277 (2019), 586-594 Food chem. Food Chemistry 0308-8146 378189 http://zaguan.unizar.es/record/84326/files/texto_completo.pdf Postprint 204039 http://zaguan.unizar.es/record/84326/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:84326 articulos driver 2020-07-16-09:09:22 ARTICLE