84349 20200716101522.0 doi 10.3389/fimmu.2019.01730 sideral 113032 ART-2019-113032 eng Garmendia, Junkal Update on the Immune Mechanisms Against Respiratory Pathogens 2019 Access copy available to the general public Unrestricted Respiratory infections pose a continuous threat to humans due to their easy dissemination via aerial transmission. As a consequence, they are leading causes of mortality and morbidity worldwide. Lower respiratory tract infections (LRTI) remained the deadliest communicable diseases causing 3 million deaths worldwide in 2016 (1). Similarly, although the number of tuberculosis (TB) deaths tends to decrease, it is still among the top 10 causes of global mortality with a yearly death burden of about 1.6 million (2). The growing emergence of bacterial antibiotic resistance is a major global challenge for the coming years, and several major respiratory pathogens are included in the WHO priority list of bacteria for which new antibiotics are urgently needed (3). In terms of target population, children under the age of five are the most susceptible hosts to a plethora of respiratory pathogens. info:eu-repo/grantAgreement/ES/MINECO/BFU2015-72190-EXP info:eu-repo/grantAgreement/ES/MINECO/RTI2018-096369-B-I00 info:eu-repo/grantAgreement/ES/MINECO/SAF2015-66520-R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 5.085 2019 IMMUNOLOGY 38 / 158 = 0.241 2019 Q1 T1 2.116 2019 Immunology and Allergy 2019 Q1 Immunology 2019 Q1 info:eu-repo/semantics/other info:eu-repo/semantics/publishedVersion (orcid)0000-0001-8841-6593 Gonzalo-Asensio, Jesús Universidad de Zaragoza 1008 630 Universidad de Zaragoza Dpto. Microb.Med.Pr.,Sal.Públ. Área Microbiología 10 (2019), 1730 [4 pp.] Front. immunol. FRONTIERS IN IMMUNOLOGY 1664-3224 236575 http://zaguan.unizar.es/record/84349/files/texto_completo.pdf Versión publicada 11242 http://zaguan.unizar.es/record/84349/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:84349 articulos driver 2020-07-16-09:27:32 ARTICLE