000085431 001__ 85431 000085431 005__ 20200716101550.0 000085431 0247_ $$2doi$$a10.1088/1367-2630/ab3dd0 000085431 0248_ $$2sideral$$a114156 000085431 037__ $$aART-2019-114156 000085431 041__ $$aeng 000085431 100__ $$aWang, Xiangrong 000085431 245__ $$aDirectionality reduces the impact of epidemics in multilayer networks 000085431 260__ $$c2019 000085431 5060_ $$aAccess copy available to the general public$$fUnrestricted 000085431 5203_ $$aOur understanding of how diseases spread has greatly benefited from advances in network modeling. However, despite of its importance for disease contagion, the directionality of edges has rarely been taken into account. On the other hand, the introduction of the multilayer framework has made it possible to deal with more complex scenarios in epidemiology such as the interaction between different pathogens or multiple strains of the same disease. In this work, we study in depth the dynamics of disease spreading in directed multilayer networks. Using the generating function approach and numerical simulations of a stochastic susceptible-infected-susceptible model, we calculate the epidemic threshold of synthetic and real-world multilayer systems and show that it is mainly determined by the directionality of the links connecting different layers, regardless of the degree distribution chosen for the layers. Our findings are of utmost interest given the ubiquitous presence of directed multilayer networks and the widespread use of disease-like spreading processes in abroad range of phenomena such as diffusion processes in social and transportation systems. 000085431 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/FIS2017-87519-P$$9info:eu-repo/grantAgreement/ES/MINECO/FIS2014-55867-P$$9info:eu-repo/grantAgreement/ES/DGA/E36-17R 000085431 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000085431 590__ $$a3.539$$b2019 000085431 591__ $$aPHYSICS, MULTIDISCIPLINARY$$b17 / 85 = 0.2$$c2019$$dQ1$$eT1 000085431 592__ $$a1.734$$b2019 000085431 593__ $$aPhysics and Astronomy (miscellaneous)$$c2019$$dQ1 000085431 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000085431 700__ $$0(orcid)0000-0002-1192-8707$$aAleta, Alberto$$uUniversidad de Zaragoza 000085431 700__ $$aLu, Dan 000085431 700__ $$0(orcid)0000-0002-0895-1893$$aMoreno, Yamir$$uUniversidad de Zaragoza 000085431 7102_ $$12004$$2405$$aUniversidad de Zaragoza$$bDpto. Física Teórica$$cÁrea Física Teórica 000085431 773__ $$g21 (2019), 093026 [14 pp.]$$pNew j. phys.$$tNew Journal of Physics$$x1367-2630 000085431 8564_ $$s913228$$uhttps://zaguan.unizar.es/record/85431/files/texto_completo.pdf$$yVersión publicada 000085431 8564_ $$s23259$$uhttps://zaguan.unizar.es/record/85431/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000085431 909CO $$ooai:zaguan.unizar.es:85431$$particulos$$pdriver 000085431 951__ $$a2020-07-16-09:45:23 000085431 980__ $$aARTICLE