000085448 001__ 85448 000085448 005__ 20230914083241.0 000085448 0247_ $$2doi$$a10.3390/plants8110455 000085448 0248_ $$2sideral$$a114508 000085448 037__ $$aART-2019-114508 000085448 041__ $$aeng 000085448 100__ $$aGiménez-Rota, Carlota 000085448 245__ $$aSupercritical carbon dioxide antisolvent fractionation for the sustainable concentration of lavandula luisieri (rozeira) Riv.- Mart antimicrobial and antioxidant compounds and comparison with its conventional extracts 000085448 260__ $$c2019 000085448 5060_ $$aAccess copy available to the general public$$fUnrestricted 000085448 5203_ $$aLavandula stoechas subsp. luisieri is a Spanish subspecies from the Lamiaceae family. Its essential oil has been traditionally used for several medical applications though little is known about other extracts. Similar to many other studies aiming to obtain traditional plant extracts to be used in different applications, this work evaluated the antioxidant and antimicrobial activities of Lavandula luisieri extracts and the correlation with their composition. Traditional hydrodistillation and ethanolic maceration were used to obtain the essential oil and the maceration extract, respectively. A green and sustainable methodology was applied to the maceration extract that was under a Supercritical Antisolvent Fractionation process to obtain a fine solid enriched in rosmarinic acid and the terpenes oleanolic and ursolic acids. Antimicrobial activities of all extracts and pure identified compounds (rosmarinic and ursolic acids) were evaluated against five bacterial strains; Listeria monocytogenes, Enterococcus faecium, Staphylococcus aureus, Salmonella Typhimurium and Escherichia coli and were compared with the pure compounds identified, rosmarinic and ursolic acids. All strains were sensitive against L. luisieri essential oil. The solid product obtained from the supercritical process was concentrated in the identified actives compared to the maceration extract, which resulted in higher antimicrobial and DPPH scavenging activities. The supercritical sustainable process provided L. luisieri compounds, with retention of their antimicrobial and antioxidant activities, in a powder exemptof organic solvents with potential application in the clinical, food or cosmetic fields. 000085448 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A06-17R$$9info:eu-repo/grantAgreement/ES/DGA/E39-17R$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2015-64049-C3-2-R 000085448 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000085448 590__ $$a2.762$$b2019 000085448 591__ $$aPLANT SCIENCES$$b58 / 234 = 0.248$$c2019$$dQ1$$eT1 000085448 592__ $$a0.877$$b2019 000085448 593__ $$aEcology$$c2019$$dQ1 000085448 593__ $$aPlant Science$$c2019$$dQ1 000085448 593__ $$aEcology, Evolution, Behavior and Systematics$$c2019$$dQ1 000085448 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000085448 700__ $$0(orcid)0000-0002-1961-8551$$aLorán, Susana$$uUniversidad de Zaragoza 000085448 700__ $$0(orcid)0000-0001-9379-8047$$aMainar, Ana M.$$uUniversidad de Zaragoza 000085448 700__ $$aHernáiz, María J. 000085448 700__ $$0(orcid)0000-0001-6375-9784$$aRota García, Carmen$$uUniversidad de Zaragoza 000085448 7102_ $$12008$$2640$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Nutrición Bromatología 000085448 7102_ $$12012$$2755$$aUniversidad de Zaragoza$$bDpto. Química Física$$cÁrea Química Física 000085448 773__ $$g8, 11 (2019), 455 [15 pp.]$$tPlants$$x2223-7747 000085448 8564_ $$s886202$$uhttps://zaguan.unizar.es/record/85448/files/texto_completo.pdf$$yVersión publicada 000085448 8564_ $$s49479$$uhttps://zaguan.unizar.es/record/85448/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000085448 909CO $$ooai:zaguan.unizar.es:85448$$particulos$$pdriver 000085448 951__ $$a2023-09-13-10:48:57 000085448 980__ $$aARTICLE