000086117 001__ 86117
000086117 005__ 20191128095707.0
000086117 0247_ $$2doi$$a10.1021/acs.langmuir.8b03378
000086117 0248_ $$2sideral$$a109813
000086117 037__ $$aART-2018-109813
000086117 041__ $$aeng
000086117 100__ $$aMartí, D.
000086117 245__ $$aAmyloid-like Fibrils from a Diphenylalanine Capped with an Aromatic Fluorenyl
000086117 260__ $$c2018
000086117 5060_ $$aAccess copy available to the general public$$fUnrestricted
000086117 5203_ $$aThe self-assembly behavior of a diphenylalanine amphiphile blocked at the C-terminus with a 9-fluorenylmethyl ester and stabilized at the N-terminus with a trifluoroacetate (TFA) anion, TFA·FF-OFm, has been examined. At low peptide concentration (0.5 mg/mL), long amyloid-like fibrils, which come from the fusion of two or more helical ribbons and/or thinner fibrils, organized in bundles or as individual entities are detected. Microbeam synchrotron radiation infrared spectroscopy has shown that TFA·FF-OFm molecules in amyloid-like fibrils arrange, forming antiparallel ß-sheets. Alteration of the experimental conditions to prioritize the thermodynamic contribution with respect to the kinetic one in the self-assembly process inhibits the organization of amyloid-like structures in favor of the formation of conventional fibrous structures. On the basis of experimental observations, a structural model where the individual antiparallel ß-sheets are oriented in parallel has been proposed for TFA·FF-OFm amyloid-like fibrils.
000086117 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E19-17R$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2013-40855-R$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/MAT2015-69367-R$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/MAT2015-69547-R
000086117 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000086117 590__ $$a3.683$$b2018
000086117 591__ $$aCHEMISTRY, PHYSICAL$$b53 / 148 = 0.358$$c2018$$dQ2$$eT2
000086117 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b55 / 172 = 0.32$$c2018$$dQ2$$eT1
000086117 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b76 / 293 = 0.259$$c2018$$dQ2$$eT1
000086117 592__ $$a1.209$$b2018
000086117 593__ $$aCondensed Matter Physics$$c2018$$dQ1
000086117 593__ $$aElectrochemistry$$c2018$$dQ1
000086117 593__ $$aSurfaces and Interfaces$$c2018$$dQ1
000086117 593__ $$aMedicine (miscellaneous)$$c2018$$dQ1
000086117 593__ $$aSpectroscopy$$c2018$$dQ1
000086117 593__ $$aMaterials Science (miscellaneous)$$c2018$$dQ1
000086117 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000086117 700__ $$aMayans, E.
000086117 700__ $$0(orcid)0000-0002-5114-080X$$aGil, A.M.
000086117 700__ $$aDíaz, A.
000086117 700__ $$0(orcid)0000-0001-8057-4861$$aJiménez, A.I.$$uUniversidad de Zaragoza
000086117 700__ $$aYousef, I.
000086117 700__ $$aKeridou, I.
000086117 700__ $$0(orcid)0000-0003-3222-0828$$aCativiela, C.$$uUniversidad de Zaragoza
000086117 700__ $$aPuiggalí, J.
000086117 700__ $$aAlemán, C.
000086117 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000086117 773__ $$g34, 50 (2018), 15551-15559$$pLangmuir$$tLangmuir$$x0743-7463
000086117 8564_ $$s1712202$$uhttps://zaguan.unizar.es/record/86117/files/texto_completo.pdf$$yPostprint
000086117 8564_ $$s299720$$uhttps://zaguan.unizar.es/record/86117/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000086117 909CO $$ooai:zaguan.unizar.es:86117$$particulos$$pdriver
000086117 951__ $$a2019-11-22-14:40:04
000086117 980__ $$aARTICLE