000086196 001__ 86196
000086196 005__ 20230830110637.0
000086196 0247_ $$2doi$$a10.1111/pedi.12802
000086196 0248_ $$2sideral$$a109800
000086196 037__ $$aART-2018-109800
000086196 041__ $$aeng
000086196 100__ $$aAgostinis-Sobrinho, C.
000086196 245__ $$aLifestyle patterns and endocrine, metabolic, and immunological biomarkers in European adolescents: The HELENA study
000086196 260__ $$c2018
000086196 5060_ $$aAccess copy available to the general public$$fUnrestricted
000086196 5203_ $$aObjective: To evaluate the association of lifestyle patterns related to physical activity (PA), sedentariness, and sleep with endocrine, metabolic, and immunological health biomarkers in European adolescents.
Methods: The present cross-sectional study comprised 3528 adolescents (1845 girls) (12.5-17.5 years) enrolled in the Healthy Lifestyle in Europe by Nutrition in Adolescence Study. Cluster analysis was performed by including body composition, PA by accelerometry, self-reported sedentary behaviors, and sleep duration. We also measured endocrine, metabolic, and immunological biomarkers.
Results: Three-cluster solutions were identified: (a) light-PA time, moderate-vigorous-PA time and sedentary time, (b) light-PA time, moderate-vigorous-PA time, sedentary time and sleep time, (c) light-PA time, moderate-vigorous-PA time, sedentary time and body composition. In addition, each cluster solution was defined as: “healthy, ” “medium healthy, ” and “unhealthy” according to the presented rating. Analysis of variance showed that overall the healthiest groups from the three clusters analyzed presented a better metabolic profile. A decision tree analysis showed that leptin had a strong association with cluster 3 in both boys and girls, high-density lipoprotein cholesterol had the strongest association with clusters 1 and 3 in boys. Cortisol had the strongest association with cluster 1. HOMA index (homeostatic model assessment) and C3 showed a strong association with cluster 3 in girls.
Conclusions: Our results support the existence of different interactions between metabolic health and lifestyle patterns related to PA, sedentariness, and sleep, with some gender-specific findings. These results highlight the importance to consider multiple lifestyle-related health factors in the assessment of adolescents'' health to plan favorable strategies.
000086196 536__ $$9info:eu-repo/grantAgreement/EUR/FP6/FOODCT-2005-007034
000086196 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000086196 590__ $$a3.347$$b2018
000086196 591__ $$aPEDIATRICS$$b12 / 124 = 0.097$$c2018$$dQ1$$eT1
000086196 591__ $$aENDOCRINOLOGY & METABOLISM$$b58 / 145 = 0.4$$c2018$$dQ2$$eT2
000086196 592__ $$a1.328$$b2018
000086196 593__ $$aEndocrinology, Diabetes and Metabolism$$c2018$$dQ1
000086196 593__ $$aPediatrics, Perinatology and Child Health$$c2018$$dQ1
000086196 593__ $$aInternal Medicine$$c2018$$dQ1
000086196 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000086196 700__ $$aGómez-Martínez, S.
000086196 700__ $$aNova, E.
000086196 700__ $$aHernandez, A.
000086196 700__ $$aLabayen, I.
000086196 700__ $$aKafatos, A.
000086196 700__ $$aGottand, F.
000086196 700__ $$aMolnár, D.
000086196 700__ $$aFerrari, M.
000086196 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000086196 700__ $$aGonzález-Gross, M.
000086196 700__ $$aMichels, N.
000086196 700__ $$0(orcid)0000-0002-3850-8235$$aRuperez, A.$$uUniversidad de Zaragoza
000086196 700__ $$aRuiz, J.R.
000086196 700__ $$aMarcos, A.
000086196 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000086196 773__ $$g20, 1 (2018), 23-31$$pPediatr. Diabetes$$tPediatric Diabetes$$x1399-543X
000086196 8564_ $$s1548493$$uhttps://zaguan.unizar.es/record/86196/files/texto_completo.pdf$$yPostprint
000086196 8564_ $$s299345$$uhttps://zaguan.unizar.es/record/86196/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000086196 909CO $$ooai:zaguan.unizar.es:86196$$particulos$$pdriver
000086196 951__ $$a2023-08-30-10:57:47
000086196 980__ $$aARTICLE