000086306 001__ 86306
000086306 005__ 20230914083237.0
000086306 0247_ $$2doi$$a10.1007/s40267-018-0590-3
000086306 0248_ $$2sideral$$a109915
000086306 037__ $$aART-2019-109915
000086306 041__ $$aeng
000086306 100__ $$0(orcid)0000-0001-9962-3387$$aFrutos Pérez-Surio, Alberto$$uUniversidad de Zaragoza
000086306 245__ $$aThe use of medicines in exceptional circumstances in Spain: adding perspective to early access
000086306 260__ $$c2019
000086306 5060_ $$aAccess copy available to the general public$$fUnrestricted
000086306 5203_ $$aThe use of medicines in exceptional circumstances refers to the use of non-authorized medicines or those used outside the authorized conditions, and comprises three different situations: (1) the use of medication in research or for compassionate use; (2) the use of foreign medicines (medicines unauthorized in one country but authorized in others); and (3) off-label use (prescription of drugs for conditions other than that for which they have been officially approved). In Spain, we intend to regulate the period between authorization and pricing through the use of therapeutic positioning reports containing standard criteria. In our opinion, the key to managing this period could be restrictive access based on the therapeutic positioning reports, prespecified agreements on acquisition cost, and restrictive time framework (for use or for decision making, e.g. orphan medicines).
000086306 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000086306 592__ $$a0.115$$b2019
000086306 593__ $$aPharmacology (medical)$$c2019$$dQ4
000086306 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000086306 700__ $$aLozano Ortiz, Roberto
000086306 7102_ $$11008$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Medic.Prevent.Salud Públ.
000086306 773__ $$g35, 2 (2019), 86-92$$pDrugs ther. perspect.$$tDrugs & therapy perspectives$$x1172-0360
000086306 8564_ $$s154050$$uhttps://zaguan.unizar.es/record/86306/files/texto_completo.pdf$$yPostprint
000086306 8564_ $$s122265$$uhttps://zaguan.unizar.es/record/86306/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000086306 909CO $$ooai:zaguan.unizar.es:86306$$particulos$$pdriver
000086306 951__ $$a2023-09-13-10:46:12
000086306 980__ $$aARTICLE