000086350 001__ 86350 000086350 005__ 20231215090951.0 000086350 0247_ $$2doi$$a10.1136/bmjopen-2019-029909 000086350 0248_ $$2sideral$$a114937 000086350 037__ $$aART-2019-114937 000086350 041__ $$aeng 000086350 100__ $$0(orcid)0000-0001-5677-1662$$aMontero-Marin, Jesús 000086350 245__ $$aAttachment-based compassion therapy and adapted mindfulness-based stress reduction for the treatment of depressive, anxious and adjustment disorders in mental health settings: A randomised controlled clinical trial protocol 000086350 260__ $$c2019 000086350 5060_ $$aAccess copy available to the general public$$fUnrestricted 000086350 5203_ $$aIntroduction Depressive, anxiety and adjustment disorders are highly prevalent among mental health outpatients. The lack of funding for mental health problems produces inefficient results and a high burden of disease. New cost-effective group interventions aimed at treating these symptoms might be an appropriate solution to reduce the healthcare burden in mental health units. Mindfulness-based interventions (MBIs) have shown significant reductions in anxious, depressive and adjustment symptomatology. Recent research highlights the influence of compassion as a key mechanism of change. However, MBIs only address compassion implicitly, whereas compassion-based protocols consider it a core aspect of psychotherapy. In this randomised controlled trial, we hypothesise that the provision of attachment-based compassion therapy (ABCT), which is a compassion-based protocol, will be more effective than mindfulness-based stress reduction (MBSR), which is a conventional MBI programme, for the treatment of depressive, anxious and adaptive symptoms in patients in mental health settings. Methods and analysis Approximately 90 patients suffering from depressive, anxious or adjustment disorders recruited from Spanish mental health settings will be randomised to receive 8 weekly 2 hours group sessions of ABCT, 8 weekly 2.5 hours group sessions of adapted MBSR (with no full-day silent retreat) or treatment as usual (TAU), with a 1:1:1 allocation rate. Patients in the ABCT and adapted MBSR groups will also receive TAU. The main outcome will be general affective distress measured by means of the Depression Anxiety Stress Scales-21'' at post-test as primary endpoint. Other outcomes will be quality of life, mindfulness, self-compassion and the use of healthcare services. There will be a 6-month follow-up assessment. Intention-to-treat analysis will be conducted using linear mixed models. Per-protocol and secondary outcome analyses will be performed. A data monitoring committee comprising the trial manager, the ABCT and MBSR teachers and an independent clinical psychologist will monitor for possible negative side effects. Ethics and dissemination Approval was obtained from the Ethics Committee of the General University Hospital of Castellón, Spain. The results will be submitted to peer-reviewed specialised journals, and brief reports will be sent to participants on request. 000086350 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B17-17R$$9info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0005 000086350 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/ 000086350 590__ $$a2.496$$b2019 000086350 591__ $$aMEDICINE, GENERAL & INTERNAL$$b52 / 165 = 0.315$$c2019$$dQ2$$eT1 000086350 592__ $$a1.247$$b2019 000086350 593__ $$aMedicine (miscellaneous)$$c2019$$dQ1 000086350 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000086350 700__ $$aCollado-Navarro, Carlos 000086350 700__ $$0(orcid)0000-0003-4842-0453$$aNavarro-Gil, Mayte$$uUniversidad de Zaragoza 000086350 700__ $$aLopez-Montoyo, Alba 000086350 700__ $$aDemarzo, Marcelo 000086350 700__ $$0(orcid)0000-0003-2088-4272$$aHerrera-Mercadal, Paola$$uUniversidad de Zaragoza 000086350 700__ $$0(orcid)0000-0002-2116-9257$$aBarcelo-Soler, Alberto 000086350 700__ $$0(orcid)0000-0002-3797-4218$$aGarcia-Campayo, Javier$$uUniversidad de Zaragoza 000086350 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría 000086350 7102_ $$14009$$2735$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicolog.Evolut.Educac 000086350 773__ $$g9, 10 (2019), e029909 1-15$$pBMJ Open$$tBMJ Open$$x2044-6055 000086350 8564_ $$s460968$$uhttps://zaguan.unizar.es/record/86350/files/texto_completo.pdf$$yVersión publicada 000086350 8564_ $$s126395$$uhttps://zaguan.unizar.es/record/86350/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000086350 909CO $$ooai:zaguan.unizar.es:86350$$particulos$$pdriver 000086350 951__ $$a2023-12-15-08:58:04 000086350 980__ $$aARTICLE