86452 20200716101518.0 doi 10.1002/adsc.201801571 sideral 110430 ART-2019-110430 eng Bottecchia, C. De novo Design of Organic Photocatalysts: Bithiophene Derivatives for the Visible-light Induced C-H Functionalization of Heteroarenes 2019 Access copy available to the general public Unrestricted Herein, we report the de novo synthesis and characterization of a series of substituted bithiophene derivatives as novel and inexpensive organic photocatalysts. DFT calculations were used to predict a priori their absorption spectra and redox potentials, which were then confirmed with empirical data. The photocatalytic activity of this novel class of organic photoredox catalyst was demonstrated in two visible-light mediated strategies for the C-H functionalization of heteroarenes. The implementation of these strategies in a continuous-flow photo-microreactor afforded moderate to excellent yields within few minutes of reaction time. Due to their straightforward synthesis, low cost and good photocatalytic properties we believe that the proposed bithiophene derivatives could be employed as a new class of organic photoredox catalysts. (Figure presented.). info:eu-repo/grantAgreement/ES/DGA/E14-17R info:eu-repo/grantAgreement/EC/H2020/641861/EU/Accelerating photoredox catalysis in continuous-flow systems/Photo4Future This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 641861-Photo4Future info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 5.851 2019 CHEMISTRY, ORGANIC 5 / 57 = 0.088 2019 Q1 T1 CHEMISTRY, APPLIED 7 / 71 = 0.099 2019 Q1 T1 1.661 2019 Organic Chemistry 2019 Q1 Catalysis 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Martín, R. Abdiaj, I. Crovini, E. Alcazar, J. (orcid)0000-0003-3514-2570 Orduna, J. Universidad de Zaragoza (orcid)0000-0001-7193-1732 Blesa, M.J. Universidad de Zaragoza Carrillo, J.R. Prieto, P. Noël, T. 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 361, 5 (2019), 945–950 Adv. synth. catal. Advanced Synthesis and Catalysis 1615-4150 406024 http://zaguan.unizar.es/record/86452/files/texto_completo.pdf Postprint 140004 http://zaguan.unizar.es/record/86452/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:86452 articulos driver 2020-07-16-09:24:37 ARTICLE