000086512 001__ 86512
000086512 005__ 20210820090345.0
000086512 0247_ $$2doi$$a10.1088/1361-6579/ab009b
000086512 0248_ $$2sideral$$a109892
000086512 037__ $$aART-2019-109892
000086512 041__ $$aeng
000086512 100__ $$aPeralta Calvo, Elena
000086512 245__ $$aOptimal fiducial points for pulse rate variability analysis from forehead and finger PPG signals
000086512 260__ $$c2019
000086512 5060_ $$aAccess copy available to the general public$$fUnrestricted
000086512 5203_ $$aObjective: The  aim  of  this  work  is  to  evaluate  and  compare  five  fiducialpoints  for  the  temporal  location  of  each  pulse  wave  from  forehead  and  fingerphotoplethysmographic  pulse  waves  signals  (PPG)  to  perform  pulse  rate  variability(PRV) analysis as a surrogate of heart rate variability (HRV) analysis.
Approach: Forehead  and  finger  PPG  signals  were  recorded  during  tilt-table  testsimultaneously  to  the  ECG.  Artifacts  were  detected  and  removed  and,  five  fiducialpoints  were  computed:  apex,  middle-amplitude  and  foot  points  of  the  PPG  signal,apex point of the first derivative signal and, the intersection point of the tangent tothe PPG waveform at the apex of the derivative PPG signal and the tangent to thefoot  of  the  PPG  pulse  defined  as  intersecting  tangents  method.   Pulse  period  (PP)time intervals series were obtained from both PPG signals and compared to the RRintervals obtained from the ECG. Heart and pulse rate variability signals (HRV andPRV) were estimated and, classical time and frequency domain indices were computed.
Main  Results: The  middle-amplitude  point  of  the  PPG  signal  (nM),  the  apexpoint  of  the  first  derivative  (n*A),  and  the  tangents  intersection  point  (nT)  are  themost  suitable  fiducial  points  for  PRV  analysis,  which  result  in  the  lowest  relativeerrors  estimated  between  PRV  and  HRV  indices,  higher  correlation  coefficients  and reliability indexes.  Statistically significant differences according to the Wilcoxon testbetween  PRV  and  HRV  signals  were  found  for  the  apex  and  foot  fiducial  points  ofthe  PPG,  as  well  as  the  lowest  agreement  between  RR  and  PP  series  according  toBland-Altman analysis.  Hence, they have been considered less accurate for variabilityanalysis.  In addition, the relative errors are significantly lower fornMandn*Afeaturesby using Friedman statistics with Bonferroni multiple-comparison test and, we proposenMas the most accurate fiducial point.  Based on our results, forehead PPG seems toprovide more reliable information for a PRV assessment than finger PPG.
Significance: The accuracy of the pulse wave detections depends on the morphologyof the PPG. There is therefore a need to widely define the most accurate fiducial pointto perform a PRV analysis under non-stationary conditions based on different PPGsensor locations and signal acquisition techniques.
000086512 536__ $$9info:eu-repo/grantAgreement/ES/UZ/UZ2018-TEC-05$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 745755-WECARMON$$9info:eu-repo/grantAgreement/EC/H2020/745755/EU/Wearable Cardiorespiratory Monitor/WECARMON$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/T39-17R-BSICoS
000086512 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000086512 590__ $$a2.309$$b2019
000086512 591__ $$aBIOPHYSICS$$b39 / 71 = 0.549$$c2019$$dQ3$$eT2
000086512 591__ $$aPHYSIOLOGY$$b43 / 81 = 0.531$$c2019$$dQ3$$eT2
000086512 591__ $$aENGINEERING, BIOMEDICAL$$b49 / 87 = 0.563$$c2019$$dQ3$$eT2
000086512 592__ $$a0.702$$b2019
000086512 593__ $$aBiomedical Engineering$$c2019$$dQ2
000086512 593__ $$aBiophysics$$c2019$$dQ2
000086512 593__ $$aPhysiology$$c2019$$dQ3
000086512 593__ $$aPhysiology (medical)$$c2019$$dQ3
000086512 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000086512 700__ $$0(orcid)0000-0001-8742-0072$$aLázaro Plaza, Jesús$$uUniversidad de Zaragoza
000086512 700__ $$0(orcid)0000-0003-1272-0550$$aBailón Luesma, Raquel$$uUniversidad de Zaragoza
000086512 700__ $$aMarozas, Vaidotas
000086512 700__ $$0(orcid)0000-0001-7285-0715$$aGil Herrando, Eduardo$$uUniversidad de Zaragoza
000086512 7102_ $$15007$$2520$$aUniversidad de Zaragoza$$bDpto. Informát.Ingenie.Sistms.$$cÁrea Ingen.Sistemas y Automát.
000086512 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000086512 773__ $$g40, 2 (2019), 025007 [15 pp.]$$pPhysiol. meas.$$tPHYSIOLOGICAL MEASUREMENT$$x0967-3334
000086512 8564_ $$s648892$$uhttps://zaguan.unizar.es/record/86512/files/texto_completo.pdf$$yPostprint
000086512 8564_ $$s86406$$uhttps://zaguan.unizar.es/record/86512/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000086512 909CO $$ooai:zaguan.unizar.es:86512$$particulos$$pdriver
000086512 951__ $$a2021-08-20-08:38:04
000086512 980__ $$aARTICLE