000087591 001__ 87591 000087591 005__ 20200716101540.0 000087591 0247_ $$2doi$$a10.1186/s12936-019-3042-1 000087591 0248_ $$2sideral$$a115799 000087591 037__ $$aART-2019-115799 000087591 041__ $$aeng 000087591 100__ $$aDomínguez García, Marta 000087591 245__ $$aImported malaria cases: the connection with the European ex-colonies 000087591 260__ $$c2019 000087591 5060_ $$aAccess copy available to the general public$$fUnrestricted 000087591 5203_ $$aBackground: Imported malaria is increasing in non-endemic areas due to the increment of international travels, migration and, probably, other unknown factors. The objective of this study was to describe the epidemiological and clinical characteristics of malaria cases in a region of Spain; analyse the possible association between the variables of interest; compare this series with others; and evaluate the characteristics of imported malaria cases according to the country of origin, particularly cases from Equatorial Guinea (Spanish ex-colony) and from the rest of sub-Saharan Africa. Methods: A descriptive observational study was carried out with a retrospective data collection of cases of malaria reported in Aragon from 1996 to 2017. Univariate and bivariate analysis of clinical-epidemiological variables was performed. In addition, an analysis of cases from sub-Saharan Africa was carried out using logistic regression, calculating odds ratio with its 95% confidence interval. Results: 609 cases of malaria were recorded in Aragon from 1996 to 2017. An autochthonous case in 2010. 50.33% were between 15 and 39 years old. 45.65% of the cases were notified of the 4-weeks 9 to 12. 82.6% reside in the main province, urban area, of which 65.4% were VFR (Visiting Friends and Relatives), 23.8% new immigrants and 10.9% travellers. The infectious Plasmodium species par excellence was Plasmodium falciparum (88%). Analysing the cases from sub-Saharan Africa (95.2% of the total), 48.1% were from Equatorial Guinea. Comparing these with the cases from the rest of sub-Saharan Africa, it was observed that the cases from the Spanish ex-colony have association with the female gender, being under 5 years old, residing in the main province (urban area) and being a new immigrant. Conclusions: The epidemiological profile of imported malaria cases can be defined as VFR between 15 and 39 years old, coming from sub-Saharan Africa, particularly from Equatorial Guinea. Immigrants education about the importance of chemoprophylaxis when travelling to visit friends and relatives, emphasizing on those who are originally from the ex-colonies of destination country, is necessary; as well as to raise awareness among health professionals to make advice in consultations, specially before summer vacations. 000087591 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/B27 000087591 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000087591 590__ $$a2.631$$b2019 000087591 591__ $$aTROPICAL MEDICINE$$b4 / 23 = 0.174$$c2019$$dQ1$$eT1 000087591 591__ $$aPARASITOLOGY$$b12 / 39 = 0.308$$c2019$$dQ2$$eT1 000087591 591__ $$aINFECTIOUS DISEASES$$b53 / 93 = 0.57$$c2019$$dQ3$$eT2 000087591 592__ $$a1.78$$b2019 000087591 593__ $$aParasitology$$c2019$$dQ1 000087591 593__ $$aInfectious Diseases$$c2019$$dQ1 000087591 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000087591 700__ $$0(orcid)0000-0002-2712-6709$$aFeja Solana, Cristina 000087591 700__ $$0(orcid)0000-0002-0091-2427$$aVergara Ugarriza, Alberto 000087591 700__ $$0(orcid)0000-0001-8820-9105$$aBartolomé Moreno, Cruz$$uUniversidad de Zaragoza 000087591 700__ $$0(orcid)0000-0003-4558-8285$$aMelús Palazón, Elena$$uUniversidad de Zaragoza 000087591 700__ $$0(orcid)0000-0002-5494-6550$$aMagallón Botaya, Rosa$$uUniversidad de Zaragoza 000087591 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000087591 773__ $$g18 (2019), 397 [8 pp.]$$pMalar. J.$$tMALARIA JOURNAL$$x1475-2875 000087591 8564_ $$s808843$$uhttps://zaguan.unizar.es/record/87591/files/texto_completo.pdf$$yVersión publicada 000087591 8564_ $$s106134$$uhttps://zaguan.unizar.es/record/87591/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000087591 909CO $$ooai:zaguan.unizar.es:87591$$particulos$$pdriver 000087591 951__ $$a2020-07-16-09:39:40 000087591 980__ $$aARTICLE