87654 20220405150414.0 doi 10.1016/j.trecan.2019.12.007 sideral 115389 ART-2020-115389 eng Ramírez-Labrada, Ariel G. The influence of lung microbiota on lung carcinogenesis, immunity and immunotherapy 2020 Access copy available to the general public Unrestricted Microbiota have emerged as key modulators of both the carcinogenic process and the immune response against cancer cells, and, thus, it seems to influence the efficacy of immunotherapy. While most studies have focused on analyzing the influence of gut microbiota, its composition substantially differs from that in the lung. Here, we describe how microbial life in the lungs is associated with host immune status in the lungs and, thus, how the identification of the microbial populations in the lower respiratory tract rather than in the gut might be key to understanding the lung carcinogenic process and to predict the efficacy of different treatments. Understanding the influence of lung microbiota on host immunity may identify new therapeutic targets and help to design new immunotherapy approaches to treat lung cancer. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 14.226 2020 ONCOLOGY 14 / 242 = 0.058 2020 Q1 T1 4.174 2020 Oncology 2020 Q1 Cancer Research 2020 Q1 info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion Isla, Dolores Artal, Angel Arias, Maykel Rezusta, Antonio Universidad de Zaragoza (orcid)0000-0001-7294-245X Pardo, Julián Universidad de Zaragoza (orcid)0000-0003-0154-0730 Gálvez, Eva M. 1011 630 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Microbiología 1011 566 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Inmunología 6, 2 (2020), P86-97 Trends cancer Trends in Cancer 2405-8033 1569785 http://zaguan.unizar.es/record/87654/files/texto_completo.pdf Versión publicada 109183 http://zaguan.unizar.es/record/87654/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:87654 articulos driver 2022-04-05-14:36:02 ARTICLE