000088191 001__ 88191
000088191 005__ 20200716101427.0
000088191 0247_ $$2doi$$a10.1016/j.diff.2019.03.001
000088191 0248_ $$2sideral$$a111208
000088191 037__ $$aART-2019-111208
000088191 041__ $$aeng
000088191 100__ $$aSánchez-Romero, N.
000088191 245__ $$aThe role of extracellular matrix on liver stem cell fate: A dynamic relationship in health and disease
000088191 260__ $$c2019
000088191 5060_ $$aAccess copy available to the general public$$fUnrestricted
000088191 5203_ $$aThe liver stem cell niche is a specialized and dynamic microenvironment with biomechanical and biochemical characteristics that regulate stem cell behavior. This is feasible due to the coordination of a complex network of secreted factors, small molecules, neural, blood inputs and extracellular matrix (ECM) components involved in the regulation of stem cell fate (self-renewal, survival, and differentiation into more mature phenotypes like hepatocytes and cholangiocytes). In this review, we describe and summarize all the major components that play essential roles in the liver stem cell niche, in particular, growth factor signaling and the biomechanical properties of the ECM.
000088191 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/C066-2014$$9info:eu-repo/grantAgreement/ES/FEDER/POCTEFA-Refbio II$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI15-00563$$9info:eu-repo/grantAgreement/ES/ISCIII/i-PFIS-IFI15-00158
000088191 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000088191 590__ $$a2.392$$b2019
000088191 592__ $$a1.017$$b2019
000088191 591__ $$aDEVELOPMENTAL BIOLOGY$$b18 / 41 = 0.439$$c2019$$dQ2$$eT2
000088191 593__ $$aCancer Research$$c2019$$dQ2
000088191 591__ $$aCELL BIOLOGY$$b146 / 195 = 0.749$$c2019$$dQ3$$eT3
000088191 593__ $$aMolecular Biology$$c2019$$dQ2
000088191 593__ $$aDevelopmental Biology$$c2019$$dQ2
000088191 593__ $$aCell Biology$$c2019$$dQ3
000088191 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion
000088191 700__ $$aSainz-Arnal, P.
000088191 700__ $$aPla-Palacín, I.
000088191 700__ $$0(orcid)0000-0002-1017-6400$$aRoyo Dachary, P.$$uUniversidad de Zaragoza
000088191 700__ $$aAlmeida, H.
000088191 700__ $$aPastor, C.
000088191 700__ $$aRubio Soto, D.
000088191 700__ $$aChico Rodriguez, M.
000088191 700__ $$aOlmedo Arbizu, E.
000088191 700__ $$0(orcid)0000-0002-4575-9067$$aBengochea Martinez, L.$$uUniversidad de Zaragoza
000088191 700__ $$0(orcid)0000-0002-7119-2244$$aSerrano-Aulló, T.$$uUniversidad de Zaragoza
000088191 700__ $$0(orcid)0000-0002-8969-7726$$aBaptista, P.M.
000088191 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000088191 7102_ $$11004$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Cirugía
000088191 7102_ $$11000$$2020$$aUniversidad de Zaragoza$$bDpto. Anat.Pat.Med.Leg.For.To.$$cArea Anatomía Patológica
000088191 773__ $$g106 (2019), 49-56$$pDifferentiation$$tDIFFERENTIATION$$x0301-4681
000088191 8564_ $$s1052480$$uhttps://zaguan.unizar.es/record/88191/files/texto_completo.pdf$$yPostprint
000088191 8564_ $$s211429$$uhttps://zaguan.unizar.es/record/88191/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000088191 909CO $$ooai:zaguan.unizar.es:88191$$particulos$$pdriver
000088191 951__ $$a2020-07-16-08:45:38
000088191 980__ $$aARTICLE