Gold-Based Nanoparticles on Amino-Functionalized Mesoporous Silica Supports as Nanozymes for Glucose Oxidation

Ortega-Liébana, M. Carmen ; Bonet-Aleta, Javier (Universidad de Zaragoza) ; Hueso, José L. ; Santamaría, Jesús (Universidad de Zaragoza)

Resumen: The transformation of glucose represents a topic of great interest at different levels. In the first place, glucose is currently conceived as a green feedstock for the sustainable production of chemicals. Secondly, the depletion of glucose at the cellular level is currently envisioned as a promising strategy to treat and alter the erratic metabolism of tumoral cells. The use of natural enzymes offers multiple advantages in terms of specificity towards the glucose substrate but may lack sufficient robustness and recyclability beyond the optimal operating conditions of these natural systems. In the present work, we have evaluated the potential use of an inorganic based nanohybrid containing gold nanoparticles supported onto ordered mesoporous supports. We have performed different assays that corroborate the enzyme-mimicking response of these inorganic surrogates towards the selective conversion of glucose into gluconic acid and hydrogen peroxide. Moreover, we conclude that these enzyme-like mimicking surrogates can operate at different pH ranges and under mild reaction conditions, can be recycled multiple times and maintain excellent catalytic response in comparison with other gold-based catalysts.

Idioma: Inglés

DOI: 10.3390/catal10030333

Año: 2020

Publicado en: Catalysts 10, 3 (2020), 333 1-15
ISSN: 2073-4344

Originalmente disponible en: Texto completo de la revista

Factor impacto JCR: 4.146 (2020)

Categ. JCR: CHEMISTRY, PHYSICAL rank: 67 / 162 = 0.414 (2020) - Q2 - T2

Factor impacto SCIMAGO: 0.8 - Physical and Theoretical Chemistry (Q2) - Catalysis (Q2)

Financiación: info:eu-repo/grantAgreement/EC/H2020/742684/EU/Catalytic Dual-Function Devices Against Cancer/CADENCE

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Ingeniería Química (Dpto. Ing.Quím.Tecnol.Med.Amb.)