000088325 001__ 88325
000088325 005__ 20240122154814.0
000088325 0247_ $$2doi$$a10.1016/j.medcli.2019.01.034
000088325 0248_ $$2sideral$$a111505
000088325 037__ $$aART-2019-111505
000088325 041__ $$aspa
000088325 100__ $$0(orcid)0000-0002-3132-2171$$aDíez-Manglano, J.
000088325 245__ $$aComparación de los índices PROFUND y PALIAR en pacientes pluripatológicos con enfermedad crónica no oncológica en fase avanzada
000088325 260__ $$c2019
000088325 5060_ $$aAccess copy available to the general public$$fUnrestricted
000088325 5203_ $$aBackground and objective: To compare the discrimination power of PROFUND and PALIAR indexes for predicting mortality in polypathological patients with advanced non-oncologic chronic disease. Material and methods: Prospective multicentre cohort study. We included polypathological patients with advanced non-oncologic chronic disease, who were admitted to internal medicine departments between July 1 st and December 31th, 2014. Data was collected from each patient on age, sex, categories of polypathology, advanced disease, comorbidity, functional and cognitive assessment, terminal illness symptoms, need for caregiver, hospitalisation in the past three and 12 months and number of drugs. We calculated the PROFUND and PALIAR indexes and conducted a 12-month follow-up. We assessed mortality with the Kaplan-Meier survival curves and the discrimination of indexes with the ROC curves. Results: We included 213 patients with a mean (standard deviation) age of 83.0 (7.0) years, 106 (49.8%) of whom were female. Mortality at six months was 40.4% and at 12 months 50.2%. Deceased patients scored higher scores on the PROFUND [11.2(4.2) vs 8.5(3.9); P <.001] and PALIAR [6.7 (4.6) vs 3.6(3.1); p < 0, 001] indexes. The discrimination of PALIAR index at six months (under the curve area 0.734 95%CI 0.665-0.803) was higher than of PROFUND, and there was no difference at 12 months. Conclusions: In polypathological patients with advanced non-oncologic chronic disease, the PALIAR index had better discrimination power than PROFUND index at 66 months and there were no differences at 12 months.
000088325 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000088325 590__ $$a1.635$$b2019
000088325 591__ $$aMEDICINE, GENERAL & INTERNAL$$b87 / 165 = 0.527$$c2019$$dQ3$$eT2
000088325 592__ $$a0.245$$b2019
000088325 593__ $$aMedicine (miscellaneous)$$c2019$$dQ3
000088325 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000088325 700__ $$aGómez-Aguirre, N.$$uUniversidad de Zaragoza
000088325 700__ $$0(orcid)0000-0002-3104-5012$$aVelilla-Marco, J.$$uUniversidad de Zaragoza
000088325 700__ $$aLambán Aranda, M.P.
000088325 700__ $$0(orcid)0000-0002-6979-9397$$ade Escalante Yangüela, B.$$uUniversidad de Zaragoza
000088325 700__ $$aFuertes Ruiz, D.
000088325 700__ $$0(orcid)0000-0001-5786-1897$$aGarcía Aranda, A.$$uUniversidad de Zaragoza
000088325 700__ $$aClemente Sarasa, C.
000088325 700__ $$aFuertes-Ruiz, D.
000088325 700__ $$aBejarano-Tello, E.
000088325 700__ $$aMunilla López, E.
000088325 700__ $$aAguirre, G.
000088325 700__ $$aBueno Castel, Carmen
000088325 700__ $$aArtajona Rodrigo, E.
000088325 700__ $$aGracia Tello, B.
000088325 700__ $$aCabrerizo García, J.L.$$uUniversidad de Zaragoza
000088325 700__ $$aYagüe Vallejo, S.$$uUniversidad de Zaragoza
000088325 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000088325 773__ $$g153, 5 (2019), 196-201$$pMed. clín.$$tMedicina clinica$$x0025-7753
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000088325 951__ $$a2024-01-22-15:32:41
000088325 980__ $$aARTICLE