000088519 001__ 88519 000088519 005__ 20210902121624.0 000088519 0247_ $$2doi$$a10.1186/s12902-019-0471-3 000088519 0248_ $$2sideral$$a117207 000088519 037__ $$aART-2020-117207 000088519 041__ $$aeng 000088519 100__ $$aWillems, R. 000088519 245__ $$aMethodology of the health economic evaluation of the Feel4Diabetes-study 000088519 260__ $$c2020 000088519 5060_ $$aAccess copy available to the general public$$fUnrestricted 000088519 5203_ $$aBACKGROUND: The clinical and economic burden of type 2 diabetes mellitus on society is rising. Effective and efficient preventive measures may stop the increasing prevalence, given that type 2 diabetes mellitus is mainly a lifestyle-driven disease. The Feel4Diabetes-study aimed to tackle unhealthy lifestyle (unhealthy diet, lack of physical activity, sedentary behaviour, and excess weight) of families with a child in the first grades of elementary school. These schools were located in regions with a relatively low socio-economic status in Belgium, Bulgaria, Finland, Greece, Hungary and Spain. Special attention was paid to families with a high risk of developing type 2 diabetes mellitus. METHODS: The aim of this paper is to describe the detailed methodology of the intervention''s cost-effectiveness analysis. Based on the health economic evaluation of the Toybox-study, both a decision analytic part and a Markov model have been designed to assess the long-term (time horizon of 70¿year with one-year¿cycles) intervention''s value for money. Data sources used for the calculation of health state incidences, transition probabilities between health states, health state costs, and health state utilities are listed. Intervention-related costs were collected by questionnaires and diaries, and attributed to either all families or high risk families only. CONCLUSIONS: The optimal use of limited resources is pivotal. The future results of the health economic evaluation of the Feel4Diabetes-study will contribute to the efficient use of those resources. 000088519 536__ $$9info:eu-repo/grantAgreement/EC/H2020/643708/EU/Developing and implementing a community-based intervention to create a more supportive social and physical environment for lifestyle changes to prevent diabetes in vulnerable families across Europe/Feel4Diabetes$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 643708-Feel4Diabetes 000088519 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000088519 590__ $$a2.763$$b2020 000088519 591__ $$aENDOCRINOLOGY & METABOLISM$$b110 / 145 = 0.759$$c2020$$dQ4$$eT3 000088519 592__ $$a0.743$$b2020 000088519 593__ $$aMedicine (miscellaneous)$$c2020$$dQ2 000088519 593__ $$aEndocrinology, Diabetes and Metabolism$$c2020$$dQ2 000088519 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000088519 700__ $$aPil, L. 000088519 700__ $$aLambrinou, C.P. 000088519 700__ $$aKivelä, J. 000088519 700__ $$aWikström, K. 000088519 700__ $$0(orcid)0000-0003-2005-8229$$aGonzalez-Gil, E.M. 000088519 700__ $$0(orcid)0000-0001-6173-5850$$aDe Miguel-Etayo, P. 000088519 700__ $$aNánási, A. 000088519 700__ $$aSemánová, C. 000088519 700__ $$aVan Stappen, V. 000088519 700__ $$aCardon, G. 000088519 700__ $$aTsochev, K. 000088519 700__ $$aIotova, V. 000088519 700__ $$aChakarova, N. 000088519 700__ $$aMakrilakis, K. 000088519 700__ $$aDafoulas, G. 000088519 700__ $$aTimpel, P. 000088519 700__ $$aSchwarz, P. 000088519 700__ $$aManios, Y. 000088519 700__ $$aAnnemans, L. 000088519 700__ $$aFeel4Diabetes, research, group 000088519 773__ $$g20, Supl 1 (2020), 14 [11 pp.]$$pBMC ENDOCRINE DISORDERS$$tBMC endocrine disorders$$x1472-6823 000088519 8564_ $$s625014$$uhttps://zaguan.unizar.es/record/88519/files/texto_completo.pdf$$yVersión publicada 000088519 8564_ $$s47732$$uhttps://zaguan.unizar.es/record/88519/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000088519 909CO $$ooai:zaguan.unizar.es:88519$$particulos$$pdriver 000088519 951__ $$a2021-09-02-08:49:27 000088519 980__ $$aARTICLE