000088532 001__ 88532
000088532 005__ 20210902121713.0
000088532 0247_ $$2doi$$a10.1186/s12969-020-0411-9
000088532 0248_ $$2sideral$$a117304
000088532 037__ $$aART-2020-117304
000088532 041__ $$aeng
000088532 100__ $$aGalindo-Zavala, R.
000088532 245__ $$aExpert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children
000088532 260__ $$c2020
000088532 5060_ $$aAccess copy available to the general public$$fUnrestricted
000088532 5203_ $$aBackground: Osteoporosis incidence in children is increasing due to the increased survival rate of patients suffering from chronic diseases and the increased use of drugs that can damage bones. Recent changes made to the definition of childhood osteoporosis, along with the lack of guidelines or national consensuses regarding its diagnosis and treatment, have resulted in a wide variability in the approaches used to treat this disease. For these reasons, the Osteogenesis Imperfecta and Childhood Osteoporosis Working Group of the Spanish Society of Pediatric Rheumatology has sounded the need for developing guidelines to standardize clinical practice with regard to this pathology. Methods: An expert panel comprised of 6 pediatricians and 5 rheumatologists carried out a qualitative literature review and provided recommendations based on evidence, when that was available, or on their own experience. The level of evidence was determined for each section using the Oxford Centre for Evidence-based Medicine (CEBM) system. A Delphi survey was conducted for those recommendations with an evidence level of IV or V. This survey was sent to all members of the SERPE. All recommendations that had a level of agreement higher or equal to 70% were included. Results: Fifty-one recommendations, categorized into eight sections, were obtained. Twenty-four of them presented an evidence level 4 or 5, and therefore a Delphi survey was conducted. This was submitted electronically and received a response rate of 40%. All recommendations submitted to the Delphi round obtained a level of agreement of 70% or higher and were therefore accepted. Conclusion: In summary, we present herein guidelines for the prevention, diagnosis and treatment of secondary childhood osteoporosis based on the available evidence and expert clinical experience. We believe it can serve as a useful tool that will contribute to the standardization of clinical practice for this pathology. Prophylactic measures, early diagnosis and a proper therapeutic approach are essential to improving bone health, not only in children and adolescents, but also in the adults they will become in the future.
000088532 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000088532 590__ $$a3.054$$b2020
000088532 591__ $$aPEDIATRICS$$b34 / 129 = 0.264$$c2020$$dQ2$$eT1
000088532 591__ $$aRHEUMATOLOGY$$b22 / 34 = 0.647$$c2020$$dQ3$$eT2
000088532 592__ $$a1.05$$b2020
000088532 593__ $$aImmunology and Allergy$$c2020$$dQ1
000088532 593__ $$aRheumatology$$c2020$$dQ1
000088532 593__ $$aPediatrics, Perinatology and Child Health$$c2020$$dQ1
000088532 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000088532 700__ $$aBou-Torrent, R.
000088532 700__ $$aMagallares-López, B.
000088532 700__ $$aMir-Perelló, C.
000088532 700__ $$aPalmou-Fontana, N.
000088532 700__ $$aSevilla-Pérez, B.
000088532 700__ $$0(orcid)0000-0001-9303-4995$$aMedrano-San Ildefonso, M.$$uUniversidad de Zaragoza
000088532 700__ $$aGonzález-Fernández , Mª.I.
000088532 700__ $$aRomán-Pascual, A.
000088532 700__ $$aAlcañiz-Rodríguez, P.
000088532 700__ $$aNieto-Gonzalez, J.C.
000088532 700__ $$aLópez-Corbeto, M.
000088532 700__ $$aGranã-Gil, J.
000088532 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000088532 773__ $$g18, 1 (2020), 20 [14 pp.]$$pPEDIATRIC RHEUMATOLOGY$$tPEDIATRIC RHEUMATOLOGY$$x1546-0096
000088532 8564_ $$s617424$$uhttps://zaguan.unizar.es/record/88532/files/texto_completo.pdf$$yVersión publicada
000088532 8564_ $$s47450$$uhttps://zaguan.unizar.es/record/88532/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000088532 909CO $$ooai:zaguan.unizar.es:88532$$particulos$$pdriver
000088532 951__ $$a2021-09-02-09:22:16
000088532 980__ $$aARTICLE