000088589 001__ 88589
000088589 005__ 20210902121701.0
000088589 0247_ $$2doi$$a10.3390/ijerph17041236
000088589 0248_ $$2sideral$$a117316
000088589 037__ $$aART-2020-117316
000088589 041__ $$aeng
000088589 100__ $$aRomero-Blanco, Cristina
000088589 245__ $$aStrength and endurance training in older women in relation to ACTN3 R577X and ACE I/D Polymorphisms
000088589 260__ $$c2020
000088589 5060_ $$aAccess copy available to the general public$$fUnrestricted
000088589 5203_ $$aThe purpose of this study is to analyze the effect of two genetic polymorphisms, ACTN3 R577X, and ACE I/D, on physical condition in a sample of active older women after a two-year training period. The sample was composed of 300 healthy women over the age of 60 who underwent a two-year training program. Adapted tests from the Senior Fitness Test were used. The genotyping of the polymorphisms was obtained from the participants’ DNA via buccal swabs. The analysis of the ACE polymorphism did not reveal differences between genotypes. The analysis of the R577X polymorphism showed a favorable effect for the ACTN3 XX genotype in tests for leg strength (p: 0.001) after training, compared to the other genotypes, and also in the analysis of the combined effect of the polymorphism (ACE II + ACTN3 RX/XX). The intragroup effect revealed an improvement in arm strength for carriers of the X allele after 24 months of training (p < 0.05). The endurance values significantly worsened in all study groups. Conclusions: The R577X polymorphism of ACTN3 may have an important role in capacities related to muscle strength, providing a beneficial effect for carriers of the X allele.
000088589 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/CB16-10-00477$$9info:eu-repo/grantAgreement/ES/ISCIII/RETICEF-RD12-043-0002$$9info:eu-repo/grantAgreement/ES/UZ/2008-BIO-01
000088589 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000088589 590__ $$a3.39$$b2020
000088589 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b41 / 176 = 0.233$$c2020$$dQ1$$eT1
000088589 591__ $$aENVIRONMENTAL SCIENCES$$b118 / 273 = 0.432$$c2020$$dQ2$$eT2
000088589 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b68 / 203 = 0.335$$c2020$$dQ2$$eT2
000088589 592__ $$a0.747$$b2020
000088589 593__ $$aHealth, Toxicology and Mutagenesis$$c2020$$dQ2
000088589 593__ $$aPublic Health, Environmental and Occupational Health$$c2020$$dQ2
000088589 593__ $$aPollution$$c2020$$dQ2
000088589 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000088589 700__ $$aArtiga-González, María Jesús
000088589 700__ $$0(orcid)0000-0001-6492-2512$$aGómez-Cabello, Alba
000088589 700__ $$aVila-Maldonado, Sara
000088589 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, José Antonio$$uUniversidad de Zaragoza
000088589 700__ $$aAra, Ignacio
000088589 700__ $$aAznar, Susana
000088589 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000088589 773__ $$g17, 4 (2020), 1236 [10 pp.]$$pInt. j. environ. res. public health$$tInternational Journal of Environmental Research and Public Health$$x1661-7827
000088589 8564_ $$s339106$$uhttps://zaguan.unizar.es/record/88589/files/texto_completo.pdf$$yVersión publicada
000088589 8564_ $$s485583$$uhttps://zaguan.unizar.es/record/88589/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000088589 909CO $$ooai:zaguan.unizar.es:88589$$particulos$$pdriver
000088589 951__ $$a2021-09-02-09:14:21
000088589 980__ $$aARTICLE