doi:10.1155/2020/9586062engPérez-Merino, P.Siedlecki, D.Remón, L.Vinas, M.Alió, J.L.Rozema, J.J.Personalized Optical Designs and Manipulating Optics: Applications on the Anterior Segment of the EyeART-2020-117589The image-forming properties of the eye can be described in terms of wave aberration. Understanding the link between aberrations and the anterior segment geometry is therefore of crucial importance for (i) comprehending how the eye works, (ii) modelling the optics of individual eyes, (iii) optimizing optical solutions, or (iv) designing surgical strategies. The eye has many innate adaptations that minimize optical aberrations. In most normal young eyes, the magnitude of aberrations of the cornea is significantly larger than for the whole eye, indicating a significant role of the crystalline lens in compensating corneal aberrations. However, due to geometrical and structural changes, this ocular compensation gets disturbed in different anterior segment conditions, such as keratoconus, presbyopia, or cataract. Keratoconus progressively degrades the corneal shape and, consequently, vision in the adolescence, with a prevalence of 0.05% in the general population. Meanwhile, presbyopia and cataract are conditions related to aging that affect the structure of the crystalline lens, one referring to a loss in accommodative amplitude (presbyopia) and the other to a progressive loss of transparency (cataract). Presbyopia affects 100% of the population older than 45¿years of age, ...2020http://zaguan.unizar.es/record/8957910.1155/2020/9586062http://zaguan.unizar.es/record/89579oai:zaguan.unizar.es:89579Journal of Ophthalmology 2020 (2020), 9586062 [3 pp]byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess