000089584 001__ 89584
000089584 005__ 20210902121627.0
000089584 0247_ $$2doi$$a10.30466/vrf.2019.107160.2549
000089584 0248_ $$2sideral$$a117606
000089584 037__ $$aART-2020-117606
000089584 041__ $$aeng
000089584 100__ $$aBelalmi, N.E.
000089584 245__ $$aEvidence of jaagsiekte sheep retrovirus-induced pulmonary adenocarcinoma in Ouled Djellal breed sheep in Algeria
000089584 260__ $$c2020
000089584 5060_ $$aAccess copy available to the general public$$fUnrestricted
000089584 5203_ $$aWe report the occurrence of lung cancer in a six months old lamb of Ouled Djellal breed from Algeria. The main clinical sign was a considerable amount of whitish foamy fluid discharge from the nostrils when the animal head was lowered and the rear end was lifted. The postmortem examination revealed the presence of enlarged, heavy and edematous lungs with diffuse or foci areas, reddish or white-gray in color. The gross and histological lesions of the lungs were compatible with pulmonary adenocarcinoma. Lung adenocarcinoma in sheep is caused by jaagsiekte sheep retrovirus (JSRV) and originated from differentiated alveolar type II cells and non-ciliated bronchiolar epithelial Clara cells. We evidenced the expression of the oncogenic JSRV by immunostaining of lung slides with specific antibodies against the JSRV envelope. The viral proteins were expressed only in the tumor cells from the affected areas. As already described in other countries, JSRV-induced lung adenocarcinoma is present in the sheep population in Algeria. (C) 2020 Urmia University. All rights reserved.
000089584 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000089584 590__ $$a1.054$$b2020
000089584 591__ $$aZOOLOGY$$b124 / 175 = 0.709$$c2020$$dQ3$$eT3
000089584 592__ $$a0.256$$b2020
000089584 593__ $$aVeterinary (miscellaneous)$$c2020$$dQ3
000089584 593__ $$aDentistry (miscellaneous)$$c2020$$dQ3
000089584 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000089584 700__ $$aSid, N.
000089584 700__ $$aBennoune, O.
000089584 700__ $$aOuhida, S.
000089584 700__ $$0(orcid)0000-0003-3792-287X$$aDe Las Heras, M.$$uUniversidad de Zaragoza
000089584 700__ $$aLeroux, C.
000089584 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000089584 773__ $$g11, 1 (2020), 93-95$$pVet. res. forum$$tVETERINARY RESEARCH FORUM$$x2008-8140
000089584 8564_ $$s896194$$uhttps://zaguan.unizar.es/record/89584/files/texto_completo.pdf$$yVersión publicada
000089584 8564_ $$s14091$$uhttps://zaguan.unizar.es/record/89584/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000089584 909CO $$ooai:zaguan.unizar.es:89584$$particulos$$pdriver
000089584 951__ $$a2021-09-02-08:50:44
000089584 980__ $$aARTICLE