000089653 001__ 89653
000089653 005__ 20230914083300.0
000089653 0247_ $$2doi$$a10.1016/j.crwh.2020.e00211
000089653 0248_ $$2sideral$$a117731
000089653 037__ $$aART-2020-117731
000089653 041__ $$aeng
000089653 100__ $$aÁlvarez-Sarrado, Leticia
000089653 245__ $$aHemoptysis as the first symptom in the diagnosis of metastatic choriocarcinoma in the third trimester of pregnancy: A case report
000089653 260__ $$c2020
000089653 5060_ $$aAccess copy available to the general public$$fUnrestricted
000089653 5203_ $$aIntroduction: Choriocarcinoma is a rare neoplasm (1/40000 pregnancies). In the context of a viable pregnancy, the incidence is even lower (1/160000). Case report: A woman in her second pregnancy was admitted at 31 + 6 weeks of gestation with hemoptysis and abnormal vaginal bleeding. Numerous placental venous lakes, bilateral pulmonary nodules and a pleural effusion were found. Pleural fluid ß-HCG levels were elevated and a brain-chest-abdominal-pelvic CT scan led to the diagnosis of a high-risk gestational trophoblastic neoplasm. A caesarean section at 32 + 1 weeks of gestation was performed. Six cycles of an EMA-CO chemotherapy regime were administered. ß-HCG levels normalized after 3 cycles. Placental histopathology confirmed the presence of a gestational choriocarcinoma. Conclusion: Choriocarcinoma is a highly aggressive tumor. In high-risk tumors, combination chemotherapy is the first-line treatment, offering high remission rates. Treatment response is evaluated by monitoring blood ß-HCG levels, which should be long-term.
000089653 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000089653 592__ $$a0.259$$b2020
000089653 593__ $$aObstetrics and Gynecology$$c2020$$dQ3
000089653 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000089653 700__ $$aGonzález-Ballano, Isabel$$uUniversidad de Zaragoza
000089653 700__ $$aHerrero-Serrano, Rebeca
000089653 700__ $$aGiménez-Molina, Claudia
000089653 700__ $$aRodríguez-Solanilla, Belén
000089653 700__ $$0(orcid)0000-0002-0306-8858$$aCampillos-Maza, José Manuel$$uUniversidad de Zaragoza
000089653 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000089653 773__ $$g27 (2020), e00211 [4 pp.]$$pCase rep. women's health$$tCase Reports in Women's Health$$x2214-9112
000089653 8564_ $$s1697857$$uhttps://zaguan.unizar.es/record/89653/files/texto_completo.pdf$$yVersión publicada
000089653 8564_ $$s49523$$uhttps://zaguan.unizar.es/record/89653/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000089653 909CO $$ooai:zaguan.unizar.es:89653$$particulos$$pdriver
000089653 951__ $$a2023-09-13-10:52:58
000089653 980__ $$aARTICLE