Measurement method of optical properties of ex vivo biological tissues of rats in the near-infrared range
Resumen: An optical fiber-based supercontinuum setup and a custom-made spectrophotometer that can measure spectra from 1100 to 2300 nm, are used to describe attenuation properties from different ex vivo rat tissues. Our method is able to differentiate between scattering and absorption coefficients in biological tissues. Theoretical assumptions combined with experimental measurements demonstrate that, in this infrared range, tissue attenuation and absorption can be accurately measured, and scattering can be described as the difference between both magnitudes. Attenuation, absorption, and scattering spectral coefficients of heart, brain, spleen, retina, and kidney are given by applying these theoretical and experimental methods. Light through these tissues is affected by high scattering, resulting in multiple absorption events, and longer wavelengths should be used to obtain lower attenuation values. It can be observed that the absorption coefficient has a similar behavior in the samples under study, with two main zones of absorption due to the water absorption bands at 1450 and 1950 nm, and with different absolute absorption values depending on the constituents of each tissue. The scattering coefficient can be determined, showing slight differences between retina and brain samples, and among heart, spleen and kidney tissues.
Idioma: Inglés
DOI: 10.1364/AO.384614
Año: 2020
Publicado en: Applied Optics 59, 13 (2020), D111-D117
ISSN: 1559-128X

Factor impacto JCR: 1.98 (2020)
Categ. JCR: OPTICS rank: 62 / 99 = 0.626 (2020) - Q3 - T2
Factor impacto SCIMAGO: 0.668 - Atomic and Molecular Physics, and Optics (Q1) - Engineering (miscellaneous) (Q1) - Electrical and Electronic Engineering (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/B08-17R
Financiación: info:eu-repo/grantAgreement/ES/DGA/T20-17R
Financiación: info:eu-repo/grantAgreement/ES/IACS/C060-2014
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/RD16-0008-0016
Financiación: info:eu-repo/grantAgreement/ES/MINECO/FIS2013-44174-P
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Área Física Aplicada (Dpto. Física Aplicada)
Área (Departamento): Área Oftalmología (Dpto. Cirugía)
Área (Departamento): Área Óptica (Dpto. Física Aplicada)


Derechos Reservados Derechos reservados por el editor de la revista


Exportado de SIDERAL (2021-09-02-09:16:24)


Visitas y descargas

Este artículo se encuentra en las siguientes colecciones:
Artículos



 Registro creado el 2020-06-16, última modificación el 2021-09-02


Versión publicada:
 PDF
Valore este documento:

Rate this document:
1
2
3
 
(Sin ninguna reseña)