000089693 001__ 89693
000089693 005__ 20230914083302.0
000089693 0247_ $$2doi$$a10.3390/diagnostics10040235
000089693 0248_ $$2sideral$$a117827
000089693 037__ $$aART-2020-117827
000089693 041__ $$aeng
000089693 100__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza
000089693 245__ $$aChoroidal changes of long-term type 1 diabetic patients without retinopathy
000089693 260__ $$c2020
000089693 5060_ $$aAccess copy available to the general public$$fUnrestricted
000089693 5203_ $$aThe aim of the study is to assess choroidal thickness (CT) and choroidal volume (CV) in 90 type 1 diabetes mellitus (DM1) patients with no diabetic retinopathy (DR) and 60 control eyes using spectral domain optical coherence tomography (SD-OCT) and swept source (SS)-OCT in the areas of the Early Treatment Diabetic Retinopathy Study (ETDRS). Mean ages were 42.93 ± 13.62 and 41.52 ± 13.05 years in the diabetic and control groups, respectively. Significant differences were obtained between both groups with Spectralis SD-OCT in all ETDRS areas and in the total CV, excluding the temporal perifoveal one. With Triton SS-OCT, statistically significant differences were obtained in the subfoveal CT and in the vertical areas. CT showed the same tendency with both OCTs, with greater CT and CV in the DM1 group than the mean values of the control group. To assess the influence of DM1 evolution in the CT modifications, DM1 patients were divided into Group 1, with less than 24 years of diagnosis, and Group 2, with =24 years of DM1 evolution. Using both OCTs, seven of the nine ETDRS areas and the CV had lower values in Group 2. CT and CV measured by OCT were higher in DM1 without DR. There is a choroidal thinning related to disease evolution in DM1. In patients with DM evolution greater than 24 years, the CT is statistically lower than in patients with less evolution of the disease.
000089693 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B08-17R$$9info:eu-repo/grantAgreement/ES/ISCIII/PI13-01124$$9info:eu-repo/grantAgreement/ES/ISCIII/RETICS-RD16-0008
000089693 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000089693 590__ $$a3.706$$b2020
000089693 591__ $$aMEDICINE, GENERAL & INTERNAL$$b45 / 167 = 0.269$$c2020$$dQ2$$eT1
000089693 592__ $$a0.622$$b2020
000089693 593__ $$aClinical Biochemistry$$c2020$$dQ3
000089693 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000089693 700__ $$0(orcid)0000-0002-9261-0302$$aPerdices, Lorena
000089693 700__ $$0(orcid)0000-0002-5621-1937$$aSanchez-Cano, Ana$$uUniversidad de Zaragoza
000089693 700__ $$0(orcid)0000-0002-2987-6351$$aAcha, Javier$$uUniversidad de Zaragoza
000089693 700__ $$aCuenca, Nicolás
000089693 700__ $$0(orcid)0000-0003-0349-9997$$aPinilla, Isabel$$uUniversidad de Zaragoza
000089693 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000089693 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología
000089693 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000089693 773__ $$g10, 4 (2020), 235 [13 pp.]$$tDiagnostics$$x2075-4418
000089693 8564_ $$s936639$$uhttps://zaguan.unizar.es/record/89693/files/texto_completo.pdf$$yVersión publicada
000089693 8564_ $$s468067$$uhttps://zaguan.unizar.es/record/89693/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000089693 909CO $$ooai:zaguan.unizar.es:89693$$particulos$$pdriver
000089693 951__ $$a2023-09-13-10:54:00
000089693 980__ $$aARTICLE