89697 20210902121714.0 doi 10.3390/app10072632 sideral 117832 ART-2020-117832 eng Martin, Carlos Universidad de Zaragoza (orcid)0000-0003-2993-5478 Update on TB vaccine pipeline 2020 Access copy available to the general public Unrestricted In addition to antibiotics, vaccination is considered among the most efficacious methods in the control and the potential eradication of infectious diseases. New safe and effective vaccines against tuberculosis (TB) could be a very important tool and are called to play a significant role in the fight against TB resistant to antimicrobials. Despite the extended use of the current TB vaccine Bacillus Calmette-Guerin (BCG), TB continues to be transmitted actively and continues to be one of the 10 most important causes of death in the world. In the last 20 years, different TB vaccines have entered clinical trials. In this paper, we review the current use of BCG and the diversity of vaccines in clinical trials and their possible indications. New TB vaccines capable of protecting against respiratory forms of the disease caused by sensitive or resistant Mycobacterium tuberculosis strains would be extremely useful tools helping to prevent the emergence of multi-drug resistance. info:eu-repo/grantAgreement/EUR/EDCTP/RIA2016V-1637 info:eu-repo/grantAgreement/ES/MICINN/RTI2018-097625-B-100 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.679 2020 PHYSICS, APPLIED 73 / 160 = 0.456 2020 Q2 T2 ENGINEERING, MULTIDISCIPLINARY 38 / 91 = 0.418 2020 Q2 T2 CHEMISTRY, MULTIDISCIPLINARY 101 / 178 = 0.567 2020 Q3 T2 MATERIALS SCIENCE, MULTIDISCIPLINARY 201 / 333 = 0.604 2020 Q3 T2 0.435 2020 Computer Science Applications 2020 Q2 Engineering (miscellaneous) 2020 Q2 Process Chemistry and Technology 2020 Q2 Instrumentation 2020 Q2 Materials Science (miscellaneous) 2020 Q2 Fluid Flow and Transfer Processes 2020 Q2 info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion Aguilo, Nacho Universidad de Zaragoza (orcid)0000-0001-7897-9173 Marinova, Dessislava Universidad de Zaragoza (orcid)0000-0001-8644-120X Gonzalo-Asensio, Jesús Universidad de Zaragoza (orcid)0000-0001-8841-6593 1011 630 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Microbiología 1011 X Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Proy. investigación HQA 10, 7 (2020), 2632 [15 pp.] Appl. sci. APPLIED SCIENCES-BASEL 2076-3417 1410149 http://zaguan.unizar.es/record/89697/files/texto_completo.pdf Versión publicada 529063 http://zaguan.unizar.es/record/89697/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:89697 articulos driver 2021-09-02-09:22:48 ARTICLE