Clinical and nutritional effectiveness of a nutritional protocol with oligomeric enteral nutrition in patients with oncology treatment-related diarrhea
Sanz-Paris, A. (Universidad de Zaragoza) ; Martinez-Trufero, J. ; Lambea-Sorrosal, J. (Universidad de Zaragoza) ; Calvo-Gracia, F. (Universidad de Zaragoza) ; Milà-Villarroel, R.
Resumen: Background: Poor nutritional status and diarrhea are common complications in cancer patients.
Methods: This multicenter, observational, prospective study evaluated the effectiveness of an oligomeric enteral nutrition (OEN) protocol in the improvement of nutritional status and reduction of diarrhea symptoms. Nutritional status was assessed with the Subjective Global Assessment (SGA), Body Mass Index (BMI) and albumin levels. Diarrhea was evaluated by the frequency and consistency of stools (Bristol Stool form scale).
Results: After 8 weeks of OEN protocol, the nutritional status improved in 48.3% of patients, with an increased proportion of patients at risk of malnourishment (+27.3%) at the expense of a decrease of moderately (-19.9%) and severely (-7.3%) malnourished patients (p < 0.001). Serum albumin and BMI significantly increased after 8 weeks of OEN treatment (p < 0.005). OEN showed a 71.1% effectiveness in the improvement of stool consistency. The mean number of stools per day significantly decreased from baseline (4.17 stools/day) to week 8 (1.42 stools/day; p = 0.0041). The nutritional status significantly improved even in those patients with persistent diarrhea.
Conclusion: The proposed OEN protocol seemed to be effective in improving the nutritional status, frequency and consistency of stools in patients with oncology treatment-related diarrhea even in persistent cases.
Idioma: Inglés
DOI: 10.3390/nu12051534
Año: 2020
Publicado en: Nutrients 12, 5 (2020), 1534 [14 pp.]
ISSN: 2072-6643
Factor impacto JCR: 5.717 (2020)
Categ. JCR: NUTRITION & DIETETICS rank: 17 / 87 = 0.195 (2020) - Q1 - T1
Factor impacto SCIMAGO: 1.417 - Nutrition and Dietetics (Q1) - Food Science (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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Methods: This multicenter, observational, prospective study evaluated the effectiveness of an oligomeric enteral nutrition (OEN) protocol in the improvement of nutritional status and reduction of diarrhea symptoms. Nutritional status was assessed with the Subjective Global Assessment (SGA), Body Mass Index (BMI) and albumin levels. Diarrhea was evaluated by the frequency and consistency of stools (Bristol Stool form scale).
Results: After 8 weeks of OEN protocol, the nutritional status improved in 48.3% of patients, with an increased proportion of patients at risk of malnourishment (+27.3%) at the expense of a decrease of moderately (-19.9%) and severely (-7.3%) malnourished patients (p < 0.001). Serum albumin and BMI significantly increased after 8 weeks of OEN treatment (p < 0.005). OEN showed a 71.1% effectiveness in the improvement of stool consistency. The mean number of stools per day significantly decreased from baseline (4.17 stools/day) to week 8 (1.42 stools/day; p = 0.0041). The nutritional status significantly improved even in those patients with persistent diarrhea.
Conclusion: The proposed OEN protocol seemed to be effective in improving the nutritional status, frequency and consistency of stools in patients with oncology treatment-related diarrhea even in persistent cases.
Idioma: Inglés
DOI: 10.3390/nu12051534
Año: 2020
Publicado en: Nutrients 12, 5 (2020), 1534 [14 pp.]
ISSN: 2072-6643
Factor impacto JCR: 5.717 (2020)
Categ. JCR: NUTRITION & DIETETICS rank: 17 / 87 = 0.195 (2020) - Q1 - T1
Factor impacto SCIMAGO: 1.417 - Nutrition and Dietetics (Q1) - Food Science (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. Exportado de SIDERAL (2024-01-30-14:18:44)
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Record created 2020-06-29, last modified 2024-01-30