000094560 001__ 94560
000094560 005__ 20240208113737.0
000094560 0247_ $$2doi$$a10.3390/ijerph17124242
000094560 0248_ $$2sideral$$a118635
000094560 037__ $$aART-2020-118635
000094560 041__ $$aeng
000094560 100__ $$aIoakeim-Skoufa, I.
000094560 245__ $$aMultimorbidity Patterns in the General Population: Results from the EpiChron Cohort Study
000094560 260__ $$c2020
000094560 5060_ $$aAccess copy available to the general public$$fUnrestricted
000094560 5203_ $$aThe correct management of patients with multimorbidity remains one of the main challenges for healthcare systems worldwide. In this study, we analyze the existence of multimorbidity patterns in the general population based on gender and age. We conducted a cross-sectional study of individuals of all ages from the EpiChron Cohort, Spain (1, 253, 292 subjects), and analyzed the presence of systematic associations among chronic disease diagnoses using exploratory factor analysis. We identified and clinically described a total of 14 different multimorbidity patterns (12 in women and 12 in men), with some relevant differences in the functions of age and gender. The number and complexity of the patterns was shown to increase with age in both genders. We identified associations of circulatory diseases with respiratory disorders, chronic musculoskeletal diseases with depression and anxiety, and a very consistent pattern of conditions whose co-occurrence is known as metabolic syndrome (hypertension, diabetes, obesity, and dyslipidaemia), among others. Our results demonstrate the potential of using real-world data to conduct large-scale epidemiological studies to assess the complex interactions among chronic conditions. This could be useful in designing clinical interventions for patients with multimorbidity, as well as recommendations for healthcare professionals on how to handle these types of patients in clinical practice.
000094560 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/B01-20R$$9info:eu-repo/grantAgreement/ES/IISA-ISCIII/CM19-00164
000094560 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000094560 590__ $$a3.39$$b2020
000094560 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b41 / 175 = 0.234$$c2020$$dQ1$$eT1
000094560 591__ $$aENVIRONMENTAL SCIENCES$$b118 / 273 = 0.432$$c2020$$dQ2$$eT2
000094560 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b68 / 202 = 0.337$$c2020$$dQ2$$eT2
000094560 592__ $$a0.747$$b2020
000094560 593__ $$aHealth, Toxicology and Mutagenesis$$c2020$$dQ2
000094560 593__ $$aPublic Health, Environmental and Occupational Health$$c2020$$dQ2
000094560 593__ $$aPollution$$c2020$$dQ2
000094560 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000094560 700__ $$0(orcid)0000-0002-5119-5093$$aPoblador-Plou, B.
000094560 700__ $$aCarmona-Pírez, J.
000094560 700__ $$0(orcid)0000-0002-3132-2171$$aDíez-Manglano, J.$$uUniversidad de Zaragoza
000094560 700__ $$aNavickas, R.
000094560 700__ $$0(orcid)0000-0003-2928-6623$$aGimeno-Feliu, L.A.$$uUniversidad de Zaragoza
000094560 700__ $$0(orcid)0000-0003-2580-2002$$aGonzález-Rubio, F.
000094560 700__ $$aJureviciene, E.
000094560 700__ $$aDambrauskas, L.
000094560 700__ $$0(orcid)0000-0002-5704-6056$$aPrados-Torres, A.
000094560 700__ $$0(orcid)0000-0002-5440-1710$$aGimeno-Miguel, A.
000094560 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000094560 773__ $$g17, 12 (2020), 4242 [15 pp.]$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827
000094560 8564_ $$s993221$$uhttps://zaguan.unizar.es/record/94560/files/texto_completo.pdf$$yVersión publicada
000094560 8564_ $$s501513$$uhttps://zaguan.unizar.es/record/94560/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000094560 909CO $$ooai:zaguan.unizar.es:94560$$particulos$$pdriver
000094560 951__ $$a2024-02-08-10:52:30
000094560 980__ $$aARTICLE