94560 20240208113737.0 doi 10.3390/ijerph17124242 sideral 118635 ART-2020-118635 eng Ioakeim-Skoufa, I. Multimorbidity Patterns in the General Population: Results from the EpiChron Cohort Study 2020 Access copy available to the general public Unrestricted The correct management of patients with multimorbidity remains one of the main challenges for healthcare systems worldwide. In this study, we analyze the existence of multimorbidity patterns in the general population based on gender and age. We conducted a cross-sectional study of individuals of all ages from the EpiChron Cohort, Spain (1, 253, 292 subjects), and analyzed the presence of systematic associations among chronic disease diagnoses using exploratory factor analysis. We identified and clinically described a total of 14 different multimorbidity patterns (12 in women and 12 in men), with some relevant differences in the functions of age and gender. The number and complexity of the patterns was shown to increase with age in both genders. We identified associations of circulatory diseases with respiratory disorders, chronic musculoskeletal diseases with depression and anxiety, and a very consistent pattern of conditions whose co-occurrence is known as metabolic syndrome (hypertension, diabetes, obesity, and dyslipidaemia), among others. Our results demonstrate the potential of using real-world data to conduct large-scale epidemiological studies to assess the complex interactions among chronic conditions. This could be useful in designing clinical interventions for patients with multimorbidity, as well as recommendations for healthcare professionals on how to handle these types of patients in clinical practice. info:eu-repo/grantAgreement/ES/DGA-FEDER/B01-20R info:eu-repo/grantAgreement/ES/IISA-ISCIII/CM19-00164 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.39 2020 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 41 / 175 = 0.234 2020 Q1 T1 ENVIRONMENTAL SCIENCES 118 / 273 = 0.432 2020 Q2 T2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 68 / 202 = 0.337 2020 Q2 T2 0.747 2020 Health, Toxicology and Mutagenesis 2020 Q2 Public Health, Environmental and Occupational Health 2020 Q2 Pollution 2020 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Poblador-Plou, B. (orcid)0000-0002-5119-5093 Carmona-Pírez, J. Díez-Manglano, J. Universidad de Zaragoza (orcid)0000-0002-3132-2171 Navickas, R. Gimeno-Feliu, L.A. Universidad de Zaragoza (orcid)0000-0003-2928-6623 González-Rubio, F. (orcid)0000-0003-2580-2002 Jureviciene, E. Dambrauskas, L. Prados-Torres, A. (orcid)0000-0002-5704-6056 Gimeno-Miguel, A. (orcid)0000-0002-5440-1710 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 17, 12 (2020), 4242 [15 pp.] Int. j. environ. res. public health International journal of environmental research and public health 1661-7827 993221 http://zaguan.unizar.es/record/94560/files/texto_completo.pdf Versión publicada 501513 http://zaguan.unizar.es/record/94560/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:94560 articulos driver 2024-02-08-10:52:30 ARTICLE