000094593 001__ 94593
000094593 005__ 20210902121742.0
000094593 0247_ $$2doi$$a10.3390/s20113158
000094593 0248_ $$2sideral$$a118654
000094593 037__ $$aART-2020-118654
000094593 041__ $$aeng
000094593 100__ $$0(orcid)0000-0003-2848-170X$$aLópez-Alonso, Borja$$uUniversidad de Zaragoza
000094593 245__ $$aReal-time impedance monitoring during electroporation processes in vegetal tissue using a high-performance generator
000094593 260__ $$c2020
000094593 5060_ $$aAccess copy available to the general public$$fUnrestricted
000094593 5203_ $$aClassical application of electroporation is carried out by using fixed protocols that do not clearly assure the complete ablation of the desired tissue. Nowadays, new methods that pursue the control of the treatment by studying the change in impedance during the applied pulses as a function of the electric field are being developed. These types of control seek to carry out the treatment in the fastest way, decreasing undesired effects and treatment time while ensuring the proper tumour ablation. The objective of this research is to determine the state of the treatment by continuously monitoring the impedance by using a novel versatile high-voltage generator and sensor system. To study the impedance dynamics in real time, the use of pulses of reduced voltage, below the threshold of reversible electroporation, is tested to characterise the state-of-the-treatment without interfering with it. With this purpose, a generator that provides both low voltage for sense tissue changes and high voltage for irreversible electroporation (IRE) was developed. In conclusion, the characterisation of the effects of electroporation in vegetal tissue, combined with the real-time monitoring of the state-of-the-treatment, will enable the provision of safer and more effective treatments.
000094593 536__ $$9info:eu-repo/grantAgreement/ES/DGA/LMP106-18$$9info:eu-repo/grantAgreement/ES/MEC/FPU16-0376$$9info:eu-repo/grantAgreement/ES/MINECO/TEC2016-78358-R
000094593 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000094593 590__ $$a3.576$$b2020
000094593 591__ $$aINSTRUMENTS & INSTRUMENTATION$$b14 / 64 = 0.219$$c2020$$dQ1$$eT1
000094593 591__ $$aCHEMISTRY, ANALYTICAL$$b26 / 83 = 0.313$$c2020$$dQ2$$eT1
000094593 591__ $$aENGINEERING, ELECTRICAL & ELECTRONIC$$b82 / 273 = 0.3$$c2020$$dQ2$$eT1
000094593 592__ $$a0.636$$b2020
000094593 593__ $$aAnalytical Chemistry$$c2020$$dQ2
000094593 593__ $$aAtomic and Molecular Physics, and Optics$$c2020$$dQ2
000094593 593__ $$aBiochemistry$$c2020$$dQ2
000094593 593__ $$aMedicine (miscellaneous)$$c2020$$dQ2
000094593 593__ $$aInformation Systems$$c2020$$dQ2
000094593 593__ $$aInstrumentation$$c2020$$dQ2
000094593 593__ $$aElectrical and Electronic Engineering$$c2020$$dQ2
000094593 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000094593 700__ $$0(orcid)0000-0001-8399-4650$$aSarnago, Héctor$$uUniversidad de Zaragoza
000094593 700__ $$0(orcid)0000-0002-1284-9007$$aLucía, Óscar$$uUniversidad de Zaragoza
000094593 700__ $$0(orcid)0000-0002-6768-5177$$aBriz, Pablo
000094593 700__ $$0(orcid)0000-0002-9655-5531$$aBurdío, José Miguel$$uUniversidad de Zaragoza
000094593 7102_ $$15008$$2785$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Tecnología Electrónica
000094593 773__ $$g20, 11 (2020), [14 pp.]$$pSensors$$tSensors (Switzerland)$$x1424-8220
000094593 8564_ $$s3383019$$uhttps://zaguan.unizar.es/record/94593/files/texto_completo.pdf$$yVersión publicada
000094593 8564_ $$s495507$$uhttps://zaguan.unizar.es/record/94593/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000094593 909CO $$ooai:zaguan.unizar.es:94593$$particulos$$pdriver
000094593 951__ $$a2021-09-02-09:43:20
000094593 980__ $$aARTICLE