doi:10.1109/ACCESS.2020.2996426engSarnago, HéctorBurdio, José M.Garcia-Sanchez, TomásMir, Lluis M.Alvarez-Gariburo, IgnacioLucia, ÓscarGaN-Based versatile waveform generator for biomedical applications of electroporationART-2020-118699Biomedical applications often require high-performance power supplies for diagnosis and treatment systems. In particular, modern electroporation techniques for cancer treatment require high-voltage generators with versatile waveform generation. In this context, sinusoidal waveform generation has been recently identified as beneficial for electrochemotherapy cancer treatments. This paper proposes the design of a high-voltage high-frequency arbitrary waveform generator taking advantage of Gallium Nitride (GaN) devices. The proposed converter has been designed and implemented, achieving a 1-MHz 2000-V output voltage. It has been electrically tested and applied to electrochemotherapy treatments in mice, demonstrating the feasibility of this proposal.2020http://zaguan.unizar.es/record/9533610.1109/ACCESS.2020.2996426http://zaguan.unizar.es/record/95336oai:zaguan.unizar.es:95336info:eu-repo/grantAgreement/ES/DGA/LMP106-18info:eu-repo/grantAgreement/ES/MINECO/TEC2016-78358-RIEEE Access 8 (2020), 97196-97203byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess