95356 20240123082600.0 doi 10.3390/ani10081255 sideral 119122 ART-2020-119122 eng Ferrer, Luis Miguel Universidad de Zaragoza (orcid)0000-0003-0042-8800 Impact of a topical anaesthesia wound management formulation on pain, inflammation and reduction of secondary infections after tail docking in lambs 2020 Access copy available to the general public Unrestricted We examined several procedures for surgical tail docking; with and without general anaesthesia (GA), including the use of a topical wound gel formulation to provide pain relief (PR) and improve healing after surgery, containing local anaesthetics lignocaine and bupivacaine, with cetrimide and adrenalin. Forty-four lambs were recruited into four equal cohorts: Groups A and C, the tail was excised with a scalpel without anaesthesia or stitches; Groups B and D, the tail was surgically excised and stitched under GA; Groups C and D wounds were immediately sprayed with PR. Behavioural observations identified that Groups A and C displayed significantly less pain-related behaviours than Groups B and D shortly after the procedure, especially if treated with PR. Similarly, the mean of days when animals showed no signs of wound infection was longer in the groups not undergoing stitching. Finally, treatment with PR appeared to reduce the cortisol response and avoided the elevation of serum amyloid A in lambs where the tail was excised without general anaesthesia. In conclusion, surgical tail-docking without GA but where wounds are immediately sprayed with PR, appears as an affordable and more welfare-appropriate method for conducting tail docking in lambs. info:eu-repo/grantAgreement/ES/DGA/A15-17R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.752 2020 VETERINARY SCIENCES 19 / 146 = 0.13 2020 Q1 T1 AGRICULTURE, DAIRY & ANIMAL SCIENCE 13 / 63 = 0.206 2020 Q1 T1 0.583 2020 Veterinary (miscellaneous) 2020 Q1 Animal Science and Zoology 2020 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Lacasta, Delia Universidad de Zaragoza (orcid)0000-0002-7822-6646 Ortín, Aurora Universidad de Zaragoza (orcid)0000-0002-0313-5926 Ramos, Juan José Universidad de Zaragoza (orcid)0000-0002-2724-2785 Tejedor, María Teresa Universidad de Zaragoza (orcid)0000-0001-5026-5144 Borobia, Marta Universidad de Zaragoza (orcid)0000-0002-0680-9957 Pérez, María Castells, Enrique Ruiz de Arcaute, Marta Universidad de Zaragoza (orcid)0000-0002-7655-2472 Ruiz, Héctor Windsor, Peter Andrew 1001 420 Universidad de Zaragoza Dpto. Anatom.,Embri.Genét.Ani. Área Genética 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 10, 8 (2020), 1255 1-14 Animals (Basel) Animals 2076-2615 884461 http://zaguan.unizar.es/record/95356/files/texto_completo.pdf Versión publicada 550898 http://zaguan.unizar.es/record/95356/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:95356 articulos driver 2024-01-23-08:21:23 ARTICLE