000095360 001__ 95360
000095360 005__ 20240122154814.0
000095360 0247_ $$2doi$$a10.3390/ijerph17145171
000095360 0248_ $$2sideral$$a119155
000095360 037__ $$aART-2020-119155
000095360 041__ $$aeng
000095360 100__ $$0(orcid)0000-0002-5119-5093$$aPoblador-Plou, B.
000095360 245__ $$aBaseline chronic comorbidity and mortality in laboratory-confirmed COVID-19 cases: Results from the PRECOVID study in Spain
000095360 260__ $$c2020
000095360 5060_ $$aAccess copy available to the general public$$fUnrestricted
000095360 5203_ $$aWe aimed to analyze baseline socio-demographic and clinical factors associated with an increased likelihood of mortality in men and women with coronavirus disease (COVID-19). We conducted a retrospective cohort study (PRECOVID Study) on all 4412 individuals with laboratory-confirmed COVID-19 in Aragon, Spain, and followed them for at least 30 days from cohort entry. We described the socio-demographic and clinical characteristics of all patients of the cohort. Age-adjusted logistic regressions models were performed to analyze the likelihood of mortality based on demographic and clinical variables. All analyses were stratified by sex. Old age, specific diseases such as diabetes, acute myocardial infarction, or congestive heart failure, and dispensation of drugs like vasodilators, antipsychotics, and potassium-sparing agents were associated with an increased likelihood of mortality. Our findings suggest that specific comorbidities, mainly of cardiovascular nature, and medications at the time of infection could explain around one quarter of the mortality in COVID-19 disease, and that women and men probably share similar but not identical risk factors. Nonetheless, the great part of mortality seems to be explained by other patient-and/or health-system-related factors. More research is needed in this field to provide the necessary evidence for the development of early identification strategies for patients at higher risk of adverse outcomes.
000095360 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/B01-20R$$9info:eu-repo/grantAgreement/ES/DGA/PI20-226
000095360 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000095360 590__ $$a3.39$$b2020
000095360 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b41 / 175 = 0.234$$c2020$$dQ1$$eT1
000095360 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b68 / 202 = 0.337$$c2020$$dQ2$$eT2
000095360 591__ $$aENVIRONMENTAL SCIENCES$$b118 / 273 = 0.432$$c2020$$dQ2$$eT2
000095360 592__ $$a0.747$$b2020
000095360 593__ $$aHealth, Toxicology and Mutagenesis$$c2020$$dQ2
000095360 593__ $$aPublic Health, Environmental and Occupational Health$$c2020$$dQ2
000095360 593__ $$aPollution$$c2020$$dQ2
000095360 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000095360 700__ $$aCarmona-Pírez, J.
000095360 700__ $$aIoakeim-Skoufa, I.
000095360 700__ $$aPoncel-Falcó, A.
000095360 700__ $$aBliek-Bueno, K.
000095360 700__ $$aCano-Del Pozo, M.
000095360 700__ $$0(orcid)0000-0003-2928-6623$$aGimeno-Feliú, L.A.$$uUniversidad de Zaragoza
000095360 700__ $$0(orcid)0000-0003-2580-2002$$aGonzález-Rubio, F.
000095360 700__ $$aAza-Pascual-salcedo, M.
000095360 700__ $$aBandrés-Liso, A.C.
000095360 700__ $$0(orcid)0000-0002-3132-2171$$aDíez-Manglano, J.$$uUniversidad de Zaragoza
000095360 700__ $$0(orcid)0000-0003-3574-3034$$aMarta-Moreno, J.$$uUniversidad de Zaragoza
000095360 700__ $$aMucherino, S.
000095360 700__ $$0(orcid)0000-0002-5440-1710$$aGimeno-Miguel, A.
000095360 700__ $$0(orcid)0000-0002-5704-6056$$aPrados-Torres, A.
000095360 700__ $$aClerencia-Sierra, M.
000095360 700__ $$0(orcid)0000-0002-4817-9527$$aCoscollar-Santaliestra, C.
000095360 700__ $$ade Alba, I.G.F.
000095360 700__ $$aMoreno-Juste, A.
000095360 700__ $$aPico-Soler, V.
000095360 700__ $$aAra-Bardají, P.
000095360 700__ $$aEpiChron, Group
000095360 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000095360 773__ $$g17, 14 (2020), 5171 1-14$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827
000095360 8564_ $$s365676$$uhttps://zaguan.unizar.es/record/95360/files/texto_completo.pdf$$yVersión publicada
000095360 8564_ $$s505000$$uhttps://zaguan.unizar.es/record/95360/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000095360 909CO $$ooai:zaguan.unizar.es:95360$$particulos$$pdriver
000095360 951__ $$a2024-01-22-15:35:06
000095360 980__ $$aARTICLE