000095370 001__ 95370
000095370 005__ 20210902121820.0
000095370 0247_ $$2doi$$a10.1186/s13028-020-00536-0
000095370 0248_ $$2sideral$$a119170
000095370 037__ $$aART-2020-119170
000095370 041__ $$aeng
000095370 100__ $$aMora-Sánchez, B.
000095370 245__ $$aEffect of a multi-citrus extract-based feed additive on the survival of rainbow trout (Oncorhynchus mykiss) following challenge with Lactococcus garvieae
000095370 260__ $$c2020
000095370 5060_ $$aAccess copy available to the general public$$fUnrestricted
000095370 5203_ $$aGrowing global concerns about antibiotic resistance have generated a considerable interest in the search for alternative environmental-friendly approaches. This study was aimed to assess the antimicrobial activity of a multi-citrus extract-based feed additive (Biocitro®) against some fish pathogens, as well as evaluate its capacity to protect rainbow trout (Oncorhynchus mykiss) to lactococcosis. A broth dilution method was used to determine the minimum inhibitory concentration (MIC) of Biocitro®, and the results showed a strong antibacterial activity against Aeromonas salmonicida, Lactococcus garvieae and Yersinia ruckeri with MIC values of 2.0 µg/mL. Afterwards, rainbow trout juveniles were fed a Biocitro®-enriched diet (750 mg/kg feed) at a daily rate of 1.5% body weight for 4 weeks, then they were challenged with L. garvieae by the cohabitation method. At the end of the experimental period, fish treated with Biocitro® showed significantly (P¿<¿0.001) improved protection against L. garvieae compared to control fish. Although further studies are needed to understand how Biocitro® increases rainbow trout resistance to L. garvieae, this feed additive could be considered as a useful alternative to chemotherapeutic treatment in aquaculture.
000095370 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000095370 590__ $$a1.695$$b2020
000095370 591__ $$aVETERINARY SCIENCES$$b58 / 146 = 0.397$$c2020$$dQ2$$eT2
000095370 592__ $$a0.607$$b2020
000095370 593__ $$aVeterinary (miscellaneous)$$c2020$$dQ1
000095370 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000095370 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000095370 700__ $$0(orcid)0000-0003-1690-5034$$aFuertes, H.
000095370 700__ $$aBalcázar, J.L.
000095370 700__ $$0(orcid)0000-0001-5095-3289$$aPérez-Sánchez, T.$$uUniversidad de Zaragoza
000095370 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000095370 773__ $$g62, 1 (2020), 38 [4 pp.]$$pActa vet. Scand.$$tActa veterinaria Scandinavica$$x0044-605X
000095370 8564_ $$s900970$$uhttps://zaguan.unizar.es/record/95370/files/texto_completo.pdf$$yVersión publicada
000095370 8564_ $$s39555$$uhttps://zaguan.unizar.es/record/95370/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000095370 909CO $$ooai:zaguan.unizar.es:95370$$particulos$$pdriver
000095370 951__ $$a2021-09-02-10:07:46
000095370 980__ $$aARTICLE