000095439 001__ 95439
000095439 005__ 20200922142031.0
000095439 0247_ $$2doi$$a10.1002/1873-3468.13610
000095439 0248_ $$2sideral$$a115278
000095439 037__ $$aART-2019-115278
000095439 041__ $$aeng
000095439 100__ $$0(orcid)0000-0002-0474-255X$$aGuio, Jorge$$uUniversidad de Zaragoza
000095439 245__ $$a2-oxoglutarate modulates the affinity of FurA for the ntcA promoter in Anabaena sp. PCC 7120
000095439 260__ $$c2019
000095439 5060_ $$aAccess copy available to the general public$$fUnrestricted
000095439 5203_ $$a2-oxoglutarate (2-OG) is a central metabolite that acts as a signaling molecule informing about the status of the carbon/nitrogen balance of the cell. In recent years, some transcriptional regulators and even two-component systems have been described as 2-OG sensors. In the nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120, two master regulators, NtcA and FurA, are deeply involved in the regulation of nitrogen metabolism. Both of them show a complex intertwined regulatory circuit to achieve a suitable regulation of nitrogen fixation. In this work, 2-OG is found to bind FurA, modulating the specific binding of FurA to the ntcA promoter. This study provides evidence of a new additional control point in the complex network controlled by the NtcA and FurA proteins.
000095439 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E35-17R$$9info:eu-repo/grantAgreement/ES/MINECO/BFU2016-77671-P
000095439 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000095439 590__ $$a3.057$$b2019
000095439 591__ $$aBIOPHYSICS$$b24 / 71 = 0.338$$c2019$$dQ2$$eT2
000095439 591__ $$aCELL BIOLOGY$$b122 / 195 = 0.626$$c2019$$dQ3$$eT2
000095439 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b154 / 297 = 0.519$$c2019$$dQ3$$eT2
000095439 592__ $$a1.948$$b2019
000095439 593__ $$aBiochemistry$$c2019$$dQ1
000095439 593__ $$aBiophysics$$c2019$$dQ1
000095439 593__ $$aStructural Biology$$c2019$$dQ1
000095439 593__ $$aGenetics$$c2019$$dQ1
000095439 593__ $$aMolecular Biology$$c2019$$dQ1
000095439 593__ $$aCell Biology$$c2019$$dQ1
000095439 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000095439 700__ $$0(orcid)0000-0002-1960-2672$$aSarasa-Buisán, Cristina$$uUniversidad de Zaragoza
000095439 700__ $$0(orcid)0000-0001-5702-4538$$aVelázquez-Campoy, Adrián$$uUniversidad de Zaragoza
000095439 700__ $$0(orcid)0000-0002-8181-2689$$aBes, María Teresa$$uUniversidad de Zaragoza
000095439 700__ $$0(orcid)0000-0001-8644-4574$$aFillat, María F$$uUniversidad de Zaragoza
000095439 700__ $$0(orcid)0000-0002-2742-3711$$aPeleato, María Luisa$$uUniversidad de Zaragoza
000095439 700__ $$0(orcid)0000-0001-6435-3540$$aSevilla, Emma$$uUniversidad de Zaragoza
000095439 7102_ $$11002$$2412$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Fisiología Vegetal
000095439 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000095439 773__ $$g594, 2 (2019), 278-289$$pFEBS lett.$$tFEBS Letters$$x0014-5793
000095439 8564_ $$s1475987$$uhttps://zaguan.unizar.es/record/95439/files/texto_completo.pdf$$yPostprint
000095439 8564_ $$s94326$$uhttps://zaguan.unizar.es/record/95439/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000095439 909CO $$ooai:zaguan.unizar.es:95439$$particulos$$pdriver
000095439 951__ $$a2020-09-22-12:17:43
000095439 980__ $$aARTICLE