95634 20210902121756.0 doi 10.1016/j.anpede.2019.05.009 sideral 118915 ART-2020-118915 eng Rodríguez-Vigil Iturrate, C Primary immune thrombocytopenia: Experience of a specialised clinic 2020 Access copy available to the general public Unrestricted Introduction: Although primary immune thrombocytopenia (ITP) is rare in childhood, it is the most frequent cause of thrombocytopenia. There have been attempts to establish risk factors to predict the progression of the disease in order to optimise its management, which has changed in recent years due to, among other reasons, specialised care. Material and methods: A retrospective, observational and analytical study was conducted on patients diagnosed with ITP over a 3-year period in a Paediatric Haematology specialist clinic. Results: From the epidemiological, clinical and analytical point of view, the characteristics of this group are similar to others. Most of the patients (23/31, 74.2%) had ITP for less than 12 months, with there being no serious complications related to the disease or the treatment received. It was established that risk factors were related to being slowly evolving (lower event free survival (EFS)) with no statistical significance, female gender, age over 10 years, leukopenia absence of initial severe thrombocytopenia, and non-specialised care. The absence of a history of infection was significantly related to a lower EFS. Conclusions: The epidemiological and analytical risk factors for a slowly evolving ITP are the same that described in the literature. Patients treated before the beginning of specialised care also had a lower EFS. These data seem to support the current recommendation that rare diseases should be managed in specialised units. (C) 2019 Published by Elsevier Espana, S.L.U. on behalf of Asociaci6n Espanola de Pediatria. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 1.5 2020 PEDIATRICS 100 / 129 = 0.775 2020 Q4 T3 0.226 2020 Pediatrics, Perinatology and Child Health 2020 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Sanz de Miguell, MP Martínez Faci, C Murillo Sanjuan, L Calvo Escribano, C García Íñiguez, JP Samper Villagrasa, MP Universidad de Zaragoza (orcid)0000-0001-5492-3191 1011 670 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Pediatría 93, 1 (2020), 16-23 An. pediatr. Anales de Pediatria 1695-4033 338772 http://zaguan.unizar.es/record/95634/files/texto_completo.pdf Versión publicada 37992 http://zaguan.unizar.es/record/95634/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:95634 articulos driver 2021-09-02-09:51:58 ARTICLE