000095916 001__ 95916
000095916 005__ 20210902121646.0
000095916 0247_ $$2doi$$a10.1038/s41598-020-57457-1
000095916 0248_ $$2sideral$$a116924
000095916 037__ $$aART-2020-116924
000095916 041__ $$aeng
000095916 100__ $$aLópez, Graciela
000095916 245__ $$aSampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study
000095916 260__ $$c2020
000095916 5060_ $$aAccess copy available to the general public$$fUnrestricted
000095916 5203_ $$aObesity and overweight in children and adolescents is increasing rapidly worldwide; however, scarce data have been reported from South America countries. With the purpose of assessing hyperlipidemia, insulin resistance and chronic inflammation, the evaluation of blood biomarkers such as glucose, lipoproteins and chronic inflammation proteins is required. In the context of the SAYCARE study, in children and adolescents (3 to 18 years) from seven South American cities, our aim was to assess the impact of pre analytical conditions on different biomarkers evaluated in 474 fresh serum samples, in different country centers. We also evaluated the stability according to time and frozen storage within this study across the concordance of the results obtained from the 49 blood samples measured in three different centers. Significant correlations as well as concordance were observed in TG, Total-C, HDL-C and glucose between Buenos Aires and São Paulo. The samples evaluated in Teresina and São Paulo presented similar results, with exception of total cholesterol. We observed acceptable concordance between Buenos Aires vs São Paulo and Teresina vs São Paulo, suggesting that samples could be processed in each of these centers. This concordance is a consequence of the strict pre analytical conditions previously established in the SAYCARE study.
000095916 536__ $$9info:eu-repo/grantAgreement/ES/MICINN-FEDER/GENUD Research Group
000095916 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000095916 590__ $$a4.379$$b2020
000095916 591__ $$aMULTIDISCIPLINARY SCIENCES$$b17 / 73 = 0.233$$c2020$$dQ1$$eT1
000095916 592__ $$a1.24$$b2020
000095916 593__ $$aMultidisciplinary$$c2020$$dQ1
000095916 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000095916 700__ $$aAssali Serruya, Raphael
000095916 700__ $$aBarchuk, Magalí
000095916 700__ $$aGaitan-Charry, Diego
000095916 700__ $$aTorres-Leal, Francisco Leonardo
000095916 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis Alberto$$uUniversidad de Zaragoza
000095916 700__ $$aDelgado, Carlos Alberto
000095916 700__ $$aBarbosa Carvalho, Heráclito
000095916 700__ $$aFerreira De Moraes, Augusto César
000095916 700__ $$aBerg, Gabriela
000095916 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000095916 773__ $$g10 (2020), 637 [7 pp]$$pSci. rep.$$tScientific Reports$$x2045-2322
000095916 8564_ $$s1055501$$uhttps://zaguan.unizar.es/record/95916/files/texto_completo.pdf$$yVersión publicada
000095916 8564_ $$s176851$$uhttps://zaguan.unizar.es/record/95916/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000095916 909CO $$ooai:zaguan.unizar.es:95916$$particulos$$pdriver
000095916 951__ $$a2021-09-02-09:03:38
000095916 980__ $$aARTICLE