MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

Benito, Juliana M. Godfrey, Laura Kojima, Kensuke Hogdal, Leah Wunderlich, Mark Geng, Huimin Marzo, Isabel Harutyunyan, Karine G. Golfman, Leonard North, Phillip Kerry, Jon Ballabio, Erica Chonghaile, Triona Ní Gonzalo, Oscar Qiu, Yihua Jeremias, Irmela Debose, LaKiesha O\u2019Brien, Eric Ma, Helen Zhou, Ping Jacamo, Rodrigo Park, Eugene Coombes, Kevin R. Zhang, Nianxiang Thomas, Deborah A. O\u2019Brien, Susan Kantarjian, Hagop M. Leverson, Joel D. Kornblau, Steven M. Andreeff, Michael Müschen, Markus Zweidler-McKay, Patrick A. Mulloy, James C. Letai, Anthony Milne, Thomas A. Konopleva, Marina MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

Cell Reports

10.1016/j.celrep.2015.12.003 2015

2015