000095977 001__ 95977 000095977 005__ 20210902121721.0 000095977 0247_ $$2doi$$a10.3390/nu12092607 000095977 0248_ $$2sideral$$a119543 000095977 037__ $$aART-2020-119543 000095977 041__ $$aeng 000095977 100__ $$aLabata-Lezaun, N. 000095977 245__ $$aEffectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis 000095977 260__ $$c2020 000095977 5060_ $$aAccess copy available to the general public$$fUnrestricted 000095977 5203_ $$aThe aim of this study was to evaluate the effectiveness of the combination of resistance training (RT) and protein supplementation (PS), compared to RT alone or combined with a placebo (plS), in the improvement of muscle strength and physical performance. The search strategy in PubMed, Cochrane Library, and Web of Sciences databases found a total of 294 studies. Once inclusion and exclusion criteria were applied, 16 studies were included for the qualitative analysis. A total of 657 healthy elderly (>60 years) participants were analysed. Finally, 15 articles were included in the quantitative analysis with one being excluded due to issues with data availability. Upper-limb, lower-limb, and handgrip strength were the primary outcomes of the meta-analysis. The secondary outcomes, related to physical performance, were Short Physical Performance Battery (SPPB), gait speed, and the five-chair-rise test (5CRT). The main results of the meta-analysis show no statistical differences for upper-limb (SMD: 0.56, 95% CI: -0.09, 1.21, p = 0.09, I2 = 68%), lower-limb (SMD: 0.00, 95% CI: -0.18, 0.18, p = 1.0, I2 = 11%), and handgrip strength (SMD: 0.03, 95% CI: -0.26, 0.32, p = 0.84, I2 = 0%) between the RT + PS and the RT alone (or combined with plS). Moreover, no statistical differences were found relating to physical performance. In view of these results, protein supplementation combined with RT does not provide additional benefits compared to RT alone or with plS in healthy elderly adults. 000095977 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000095977 590__ $$a5.717$$b2020 000095977 591__ $$aNUTRITION & DIETETICS$$b17 / 88 = 0.193$$c2020$$dQ1$$eT1 000095977 592__ $$a1.417$$b2020 000095977 593__ $$aNutrition and Dietetics$$c2020$$dQ1 000095977 593__ $$aFood Science$$c2020$$dQ1 000095977 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion 000095977 700__ $$aLlurda-Almuzara, L. 000095977 700__ $$aLópez-de-Celis, C. 000095977 700__ $$aRodríguez-Sanz, J. 000095977 700__ $$aGonzález-Rueda, V. 000095977 700__ $$0(orcid)0000-0001-7667-2178$$aHidalgo-García, C.$$uUniversidad de Zaragoza 000095977 700__ $$0(orcid)0000-0002-9191-9033$$aMuñiz-Pardos, B.$$uUniversidad de Zaragoza 000095977 700__ $$aPérez-Bellmunt, A. 000095977 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor. 000095977 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia 000095977 773__ $$g12, 9 (2020), 2607 [16 pp]$$pNUTRIENTS$$tNutrients$$x2072-6643 000095977 8564_ $$s807671$$uhttps://zaguan.unizar.es/record/95977/files/texto_completo.pdf$$yVersión publicada 000095977 8564_ $$s492190$$uhttps://zaguan.unizar.es/record/95977/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000095977 909CO $$ooai:zaguan.unizar.es:95977$$particulos$$pdriver 000095977 951__ $$a2021-09-02-09:28:39 000095977 980__ $$aARTICLE