Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of a-Synuclein Protect Against Diverse a-Synuclein Mediated Dysfunctions

Tóth, Gergely Neumann, Thomas Berthet, Amandine Masliah, Eliezer Spencer, Brian Tao, Jiahui Jobling, Michael F. Gardai, Shyra J. Bertoncini, Carlos W. Cremades, Nunilo Bova, Michael Ballaron, Stephen Chen, Xiao-Hua Mao, Wenxian Nguyen, Phuong Tabios, Mariano C. Tambe, Mitali A. Rochet, Jean-Christophe Junker, Hans-Dieter Schwizer, Daniel Sekul, Renate Ott, Inge Anderson, John P. Szoke, Balazs Hoffman, Wherly Christodoulou, John Yednock, Ted Agard, David A. Schenk, Dale McConlogue, Lisa Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of a-Synuclein Protect Against Diverse a-Synuclein Mediated Dysfunctions

Sci. rep.

10.1038/s41598-019-52598-4 2019

2019