000096111 001__ 96111
000096111 005__ 20210902121838.0
000096111 0247_ $$2doi$$a10.1186/s12911-020-01280-1
000096111 0248_ $$2sideral$$a120757
000096111 037__ $$aART-2020-120757
000096111 041__ $$aeng
000096111 100__ $$aMarcilly, R.
000096111 245__ $$aHow to interact with medical terminologies? Formative usability evaluations comparing three approaches for supporting the use of MedDRA by pharmacovigilance specialists
000096111 260__ $$c2020
000096111 5060_ $$aAccess copy available to the general public$$fUnrestricted
000096111 5203_ $$aBackground: Medical terminologies are commonly used in medicine. For instance, to answer a pharmacovigilance question, pharmacovigilance specialists (PVS) search in a pharmacovigilance database for reports in relation to a given drug. To do that, they first need to identify all MedDRA terms that might have been used to code an adverse reaction in the database, but terms may be numerous and difficult to select as they may belong to different parts of the hierarchy. In previous studies, three tools have been developed to help PVS identify and group all relevant MedDRA terms using three different approaches: forms, structured query-builder, and icons. Yet, a poor usability of the tools may increase PVS' workload and reduce their performance. This study aims to evaluate, compare and improve the three tools during two rounds of formative usability evaluation. 
Methods: First, a cognitive walkthrough was performed. Based on the design recommendations obtained from this evaluation, designers made modifications to their tools to improve usability. Once this re-engineering phase completed, six PVS took part in a usability test: difficulties, errors and verbalizations during their interaction with the three tools were collected. Their satisfaction was measured through the System Usability Scale. The design recommendations issued from the tests were used to adapt the tools. 
Results: All tools had usability problems related to the lack of guidance in the graphical user interface (e.g., unintuitive labels). In two tools, the use of the SNOMED CT to find MedDRA terms hampered their use because French PVS were not used to it. For the most obvious and common terms, the icons-based interface would appear to be more useful. For the less frequently used MedDRA terms or those distributed in different parts of the hierarchy, the structured query-builder would be preferable thanks to its great power and flexibility. The form-based tool seems to be a compromise. 
Conclusion: These evaluations made it possible to identify the strengths of each tool but also their weaknesses to address them before further evaluation. Next step is to assess the acceptability of tools and the expressiveness of their results to help identify and group MedDRA terms.
000096111 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000096111 590__ $$a2.796$$b2020
000096111 591__ $$aMEDICAL INFORMATICS$$b18 / 30 = 0.6$$c2020$$dQ3$$eT2
000096111 592__ $$a0.777$$b2020
000096111 593__ $$aHealth Policy$$c2020$$dQ2
000096111 593__ $$aHealth Informatics$$c2020$$dQ2
000096111 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000096111 700__ $$aDouze, L.
000096111 700__ $$aFerré, S.
000096111 700__ $$aAudeh, B.
000096111 700__ $$0(orcid)0000-0003-4239-8785$$aBobed, C.$$uUniversidad de Zaragoza
000096111 700__ $$aLillo-Le Louët, A.
000096111 700__ $$aLamy, J.B.
000096111 700__ $$aBousquet, C.
000096111 7102_ $$15007$$2570$$aUniversidad de Zaragoza$$bDpto. Informát.Ingenie.Sistms.$$cÁrea Lenguajes y Sistemas Inf.
000096111 773__ $$g20, 1 (2020), 261 [15 pp]$$pBMC Medical Informatics and Decision Making$$tBMC Medical Informatics and Decision Making$$x1472-6947
000096111 8564_ $$s950865$$uhttps://zaguan.unizar.es/record/96111/files/texto_completo.pdf$$yVersión publicada
000096111 8564_ $$s52005$$uhttps://zaguan.unizar.es/record/96111/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000096111 909CO $$ooai:zaguan.unizar.es:96111$$particulos$$pdriver
000096111 951__ $$a2021-09-02-10:21:51
000096111 980__ $$aARTICLE