000096204 001__ 96204
000096204 005__ 20230519145349.0
000096204 0247_ $$2doi$$a10.1111/tri.13759
000096204 0248_ $$2sideral$$a120495
000096204 037__ $$aART-2021-120495
000096204 041__ $$aeng
000096204 100__ $$aAbd ElHafeez, S.
000096204 245__ $$aThe association of living donor source with patient and graft survival among kidney transplant recipients in the ERA-EDTA Registry – a retrospective study
000096204 260__ $$c2021
000096204 5060_ $$aAccess copy available to the general public$$fUnrestricted
000096204 5203_ $$aIn this study we aimed to compare patient and graft survival of kidney transplant recipients who received a kidney from a living-related donor (LRD) or living-unrelated donor (LUD). Adult patients in the ERA-EDTA Registry who received their first kidney transplant in 1998–2017 were included. Ten-year patient and graft survival were compared between LRD and LUD transplants using Cox regression analysis. In total, 14 370 patients received a kidney from a living donor. Of those, 9212 (64.1%) grafts were from a LRD, 5063 (35.2%) from a LUD and for 95 (0.7%), the donor type was unknown. Unadjusted five-year risks of death and graft failure (including death as event) were lower for LRD transplants than for LUD grafts: 4.2% (95% confidence interval [CI]: 3.7–4.6) and 10.8% (95% CI: 10.1–11.5) versus 6.5% (95% CI: 5.7–7.4) and 12.2% (95% CI: 11.2–13.3), respectively. However, after adjusting for potential confounders, associations disappeared with hazard ratios of 0.99 (95% CI: 0.87–1.13) for patient survival and 1.03 (95% CI: 0.94–1.14) for graft survival. Unadjusted risk of death-censored graft failure was similar, but after adjustment, it was higher for LUD transplants (1.19; 95% CI: 1.04–1.35). In conclusion, patient and graft survival of LRD and LUD kidney transplant recipients was similar, whereas death-censored graft failure was higher in LUD. These findings confirm the importance of both living kidney donor types.
000096204 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000096204 590__ $$a3.842$$b2021
000096204 591__ $$aSURGERY$$b46 / 214 = 0.215$$c2021$$dQ1$$eT1
000096204 591__ $$aTRANSPLANTATION$$b10 / 26 = 0.385$$c2021$$dQ2$$eT2
000096204 594__ $$a4.3$$b2021
000096204 592__ $$a1.005$$b2021
000096204 593__ $$aTransplantation$$c2021$$dQ1
000096204 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000096204 700__ $$aNoordzij, M.
000096204 700__ $$aKramer, A.
000096204 700__ $$aBell, S.
000096204 700__ $$aSavoye, E.
000096204 700__ $$0(orcid)0000-0001-9466-3902$$aAbad Diez, J.M.$$uUniversidad de Zaragoza
000096204 700__ $$aLundgren, T.
000096204 700__ $$aReisæter, A.V.
000096204 700__ $$aKerschbaum, J.
000096204 700__ $$aSantiuste de Pablos, C.
000096204 700__ $$aOrtiz, F.
000096204 700__ $$aCollart, F.
000096204 700__ $$aPalsson, R.
000096204 700__ $$aArici, M.
000096204 700__ $$aHeaf, J.G.
000096204 700__ $$aMassy, Z.A.
000096204 700__ $$aJager, K.J.
000096204 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000096204 773__ $$g34, 1 (2021), 76-86$$pTranspl. int.$$tTRANSPLANT INTERNATIONAL$$x0934-0874
000096204 8564_ $$s468728$$uhttps://zaguan.unizar.es/record/96204/files/texto_completo.pdf$$yVersión publicada
000096204 8564_ $$s38521$$uhttps://zaguan.unizar.es/record/96204/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000096204 909CO $$ooai:zaguan.unizar.es:96204$$particulos$$pdriver
000096204 951__ $$a2023-05-18-13:25:32
000096204 980__ $$aARTICLE