doi:10.1038/s41597-019-0109-3engAnguita-Ruiz, AugustoPlaza-Diaz, JulioRuiz-Ojeda, Francisco JavierRuperez, Azahara I.Leis, RosauraBueno, GloriaGil-Campos, MercedesVazquez-Cobela, RocíoCanete, RamónMoreno, Luis A.Gil, ÁngelAguilera, Concepción MaríaX chromosome genetic data in a Spanish children cohort, dataset description and analysis pipelineART-2019-113034X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region.2019http://zaguan.unizar.es/record/9625510.1038/s41597-019-0109-3http://zaguan.unizar.es/record/96255oai:zaguan.unizar.es:96255info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI051968info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI1102042info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI1600871info:eu-repo/grantAgreement/ES/ISCIII/i-PFIS-IFI17-00048info:eu-repo/grantAgreement/ES/ISCIII/RETICS-RD12-0026-0015SCIENTIFIC DATA 6 (2019), 130 [10 pp]byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess