000097140 001__ 97140 000097140 005__ 20210902121847.0 000097140 0247_ $$2doi$$a10.1186/s12885-020-07558-x 000097140 0248_ $$2sideral$$a121114 000097140 037__ $$aART-2020-121114 000097140 041__ $$aeng 000097140 100__ $$aMuñoz-Alcaraz, M.N. 000097140 245__ $$aEfficacy and efficiency of a new therapeutic approach based on activity-oriented proprioceptive antiedema therapy (TAPA) for edema reduction and improved occupational performance in the rehabilitation of breast cancer-related arm lymphedema in women: a controlled, randomized clinical trial 000097140 260__ $$c2020 000097140 5060_ $$aAccess copy available to the general public$$fUnrestricted 000097140 5203_ $$aBackground: Breast cancer (BC) is a major public health issue. More than one out of five women treated for breast cancer will develop lymphedema in an upper extremity. Current evidence advocates transdisciplinary oncological rehabilitation. Therefore, research in this area is necessary since limited consensus having been reached with regard to the basic essential components of this rehabilitation. Consensus has, however, been reached on the use of decongestive lymphedema therapy (DLT), but due to a lack of tests, the necessary dosages are unknown and its level is moderately strong. This study attempts to verify both the efficacy of activity-oriented proprioceptive antiedema therapy (TAPA), as compared to conventional treatments such as DLT or Complex Physical Therapy (CPT), as well as its efficiency in terms of cost-effectiveness, for patients affected by breast cancer-related arm lymphedema. Methods: Controlled, randomized clinical trial with dual stratification, two parallel arms, longitudinal and single blind. 64 women with breast cancer-related arm lymphedema will take part in the study. The experimental group intervention will be the same for stage I and II, and will consist of neuro-dynamic exercises oriented to the activity, proprioceptive neuromuscular facilitation activities and proprioceptive anti-edema bandaging. The control group intervention, depending on the stage, will consist of preventive measures, skin care and exercise-prescribed training in the lymphedema workshop as well as compression garments (Stage I) or conservative Complex Decongestive Therapy treatment (skin care, multi-layer bandaging, manual lymphatic drainage and massage therapy) (Stage II). Results: Sociodemographic and clinical variables will be collected for the measurement of edema volume and ADL performance. Statistical analysis will be performed on intent to treat. Discussion: It has been recommended that patient training be added to DLT, as well as a re-designing of patient lifestyles and the promotion of health-related aspects. In addition, clinical trials should be undertaken to assess neural mobilization techniques and proprioceptive neuromuscular facilitation should be included in the therapy. Cohesive bandaging will also be performed as an early form of pressotherapy. The proposed study combines all of these aspects in order to increased comfort and promote the participation of individuals with lymphedema in everyday situations. Limitations: The authors have proposed the assessment of the experimental treatment for stages I and II. One possible limitation is the lack of awareness of whether or not this treatment would be effective for other stages as well as the concern for proper hand cleansing during use of bandages, given the current COVID-19 pandemic situation. Trial registration: This trial was registered in ClinicalTrials.gov (NCT03762044). Date of registration: 23 November 2018. Prospectively Registered. 000097140 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B21-17R-GAIAP$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/Another way to make Europe 000097140 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000097140 590__ $$a4.43$$b2020 000097140 591__ $$aONCOLOGY$$b109 / 242 = 0.45$$c2020$$dQ2$$eT2 000097140 592__ $$a1.358$$b2020 000097140 593__ $$aCancer Research$$c2020$$dQ2 000097140 593__ $$aOncology$$c2020$$dQ2 000097140 593__ $$aGenetics$$c2020$$dQ2 000097140 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000097140 700__ $$aPérula-de-Torres, L.Á. 000097140 700__ $$aSerrano-Merino, J. 000097140 700__ $$aJiménez-Vílchez, A.J. 000097140 700__ $$aOlmo-Carmona, M.V. 000097140 700__ $$aMuñoz-García, M.T. 000097140 700__ $$0(orcid)0000-0001-8820-9105$$aBartolomé-Moreno, C.$$uUniversidad de Zaragoza 000097140 700__ $$0(orcid)0000-0001-6565-9699$$aOliván-Blázquez, B.$$uUniversidad de Zaragoza 000097140 700__ $$0(orcid)0000-0002-5494-6550$$aMagallón-Botaya, R.$$uUniversidad de Zaragoza 000097140 7102_ $$14009$$2740$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Social 000097140 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000097140 773__ $$g20, 1 (2020), 1074 [11 pp]$$pBMC CANCER$$tBMC CANCER$$x1471-2407 000097140 8564_ $$s1228042$$uhttps://zaguan.unizar.es/record/97140/files/texto_completo.pdf$$yVersión publicada 000097140 8564_ $$s45764$$uhttps://zaguan.unizar.es/record/97140/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000097140 909CO $$ooai:zaguan.unizar.es:97140$$particulos$$pdriver 000097140 951__ $$a2021-09-02-10:27:36 000097140 980__ $$aARTICLE