000097187 001__ 97187
000097187 005__ 20210902121907.0
000097187 0247_ $$2doi$$a10.1136/bmjopen-2019-035238
000097187 0248_ $$2sideral$$a121099
000097187 037__ $$aART-2020-121099
000097187 041__ $$aeng
000097187 100__ $$aJiménez-Pericás, F.
000097187 245__ $$aHigher incidence of adverse events in isolated patients compared with non-isolated patients: A cohort study
000097187 260__ $$c2020
000097187 5060_ $$aAccess copy available to the general public$$fUnrestricted
000097187 5203_ $$aObjective
To determine whether isolated patients admitted to hospital have a higher incidence of adverse events (AEs), to identify their nature, impact and preventability.
Design
Prospective cohort study with isolated and non-isolated patients.
Setting
One public university hospital in the Valencian Community (southeast Spain).
Participants
We consecutively collected 400 patients, 200 isolated and 200 non-isolated, age =18 years old, to match according to date of entry, admission department, sex, age (±5 years) and disease severity from April 2017 to October 2018. Exclusion criteria: patients age <18 years old and/or reverse isolation patients.
Primary and secondary outcome measures
The primary outcome as the AE, defined according to the National Study of Adverse Effects linked to Hospitalisation (Estudio Nacional Sobre los Efectos Adversos) criteria. Cumulative incidence rates and AE incidence density rates were calculated.
Results
The incidence of isolated patients with AEs 16.5% (95% CI 11.4% to 21.6%) compared with 9.5% (95% CI 5.4% to 13.6%) in non-isolated (p<0.03). The incidence density of patients with AEs among isolated patients was 11.8 per 1000?days/patient (95%?CI 7.8 to 15.9) compared with 4.3 per 1000?days/patient (95%?CI 2.4 to 6.3) among non-isolated patients (p<0.001). The incidence of AEs among isolated patients was 18.5% compared with 11% for non-isolated patients (p<0.09). Among the 37 AEs detected in 33 isolated patients, and the 22 AEs detected in 19 non-isolated patients, most corresponded to healthcare-associated infections (HAIs) for both isolated and non-isolated patients (48.6% vs 45.4%). There were significant differences with respect to the preventability of AEs, (67.6% among isolated patients compared with 52.6% among non-isolated patients).
Conclusions
AEs were significantly higher in isolated patients compared with non-isolated patients, more than half being preventable and with HAIs as the primary cause. It is essential to improve training and the safety culture of healthcare professionals relating to the care provided to this type of patient.
000097187 536__ $$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/PI13-01921
000097187 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000097187 590__ $$a2.692$$b2020
000097187 591__ $$aMEDICINE, GENERAL & INTERNAL$$b64 / 169 = 0.379$$c2020$$dQ2$$eT2
000097187 592__ $$a1.131$$b2020
000097187 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000097187 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000097187 700__ $$aGea Velázquez De Castro, M.T.
000097187 700__ $$aPastor-Valero, M.
000097187 700__ $$0(orcid)0000-0001-9714-8105$$aAibar Remón, C.$$uUniversidad de Zaragoza
000097187 700__ $$aMiralles, J.J.
000097187 700__ $$aMeyer García, M.D.C.
000097187 700__ $$aAranaz Andrés, J.M.
000097187 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000097187 773__ $$g10, 10 (2020), e035238 [9 pp]$$pBMJ Open$$tBMJ open$$x2044-6055
000097187 8564_ $$s311258$$uhttps://zaguan.unizar.es/record/97187/files/texto_completo.pdf$$yVersión publicada
000097187 8564_ $$s129758$$uhttps://zaguan.unizar.es/record/97187/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000097187 909CO $$ooai:zaguan.unizar.es:97187$$particulos$$pdriver
000097187 951__ $$a2021-09-02-10:40:01
000097187 980__ $$aARTICLE