000097426 001__ 97426
000097426 005__ 20210902121925.0
000097426 0247_ $$2doi$$a10.3390/nu12123841
000097426 0248_ $$2sideral$$a121691
000097426 037__ $$aART-2020-121691
000097426 041__ $$aeng
000097426 100__ $$0(orcid)0000-0001-6899-5938$$aSeral-Cortes, M.$$uUniversidad de Zaragoza
000097426 245__ $$aInteraction effect of the mediterranean diet and an obesity genetic risk score on adiposity and metabolic syndrome in adolescents: The HELENA study
000097426 260__ $$c2020
000097426 5060_ $$aAccess copy available to the general public$$fUnrestricted
000097426 5203_ $$aObesity and metabolic syndrome (MetS) are worldwide major health challenges. The Mediterranean diet (MD) is associated with a better cardiometabolic profile, but these beneficial effects may be influenced by genetic variations, modulating the predisposition to obesity or MetS. The aim was to assess whether interaction effects occur between an obesity genetic risk score (obesity-GRS) and the MD on adiposity and MetS in European adolescents. Multiple linear regression models were used to assess the interaction effects of an obesity-GRS and the MD on adiposity and MetS and its components. Interaction effects between the MD on adiposity and MetS were observed in both sex groups (p < 0.05). However, those interaction effects were only expressed in a certain number of adolescents, when a limited number of risk alleles were present. Regarding adiposity, a total of 51.1% males and 98.7% females had lower body mass index (BMI) as a result of higher MD adherence. Concerning MetS, only 9.9% of males with higher MD adherence had lower MetS scores. However, the same effect was observed in 95.2% of females. In conclusion, obesity-related genotypes could modulate the relationship between MD adherence and adiposity and MetS in European adolescents; the interaction effect was higher in females than in males.
000097426 536__ $$9info:eu-repo/grantAgreement/EC/FP6/7034/EU/Healthy Lifestyle in Europe by Nutrition in Adolescence/7034$$9info:eu-repo/grantAgreement/EC/H2020/801586/EU/International Doctoral Programme for Talent Attraction to the Campus of International Excellence of the Ebro Valley/IberusTalent$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 801586-IberusTalent$$9info:eu-repo/grantAgreement/ES/ISCIII/CIBERObn$$9info:eu-repo/grantAgreement/ES/MINECO/RYC-2010-05957$$9info:eu-repo/grantAgreement/ES/MINECO/RYC-2011-09011
000097426 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000097426 590__ $$a5.717$$b2020
000097426 591__ $$aNUTRITION & DIETETICS$$b17 / 88 = 0.193$$c2020$$dQ1$$eT1
000097426 592__ $$a1.417$$b2020
000097426 593__ $$aNutrition and Dietetics$$c2020$$dQ1
000097426 593__ $$aFood Science$$c2020$$dQ1
000097426 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000097426 700__ $$aSabroso-Lasa, S.
000097426 700__ $$0(orcid)0000-0001-6173-5850$$aDe Miguel-Etayo, P.
000097426 700__ $$aGonzalez-Gross, M.
000097426 700__ $$aGesteiro, E.
000097426 700__ $$aMolina-Hidalgo, C.
000097426 700__ $$aDe Henauw, S.
000097426 700__ $$aErhardt, É.
000097426 700__ $$aCensi, L.
000097426 700__ $$aManios, Y.
000097426 700__ $$aKaraglani, E.
000097426 700__ $$aWidhalm, K.
000097426 700__ $$aKafatos, A.
000097426 700__ $$aBeghin, L.
000097426 700__ $$aMeirhaeghe, A.
000097426 700__ $$aSalazar-Tortosa, D.
000097426 700__ $$aRuiz, J.R.
000097426 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000097426 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban, L.M.
000097426 700__ $$aLabayen, I.
000097426 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000097426 773__ $$g12, 12 (2020), 1-14$$pNUTRIENTS$$tNutrients$$x2072-6643
000097426 8564_ $$s486925$$uhttps://zaguan.unizar.es/record/97426/files/texto_completo.pdf$$yVersión publicada
000097426 8564_ $$s473959$$uhttps://zaguan.unizar.es/record/97426/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000097426 909CO $$ooai:zaguan.unizar.es:97426$$particulos$$pdriver
000097426 951__ $$a2021-09-02-10:51:10
000097426 980__ $$aARTICLE