000097440 001__ 97440
000097440 005__ 20210902121844.0
000097440 0247_ $$2doi$$a10.1371/journal.pone.0243740
000097440 0248_ $$2sideral$$a121738
000097440 037__ $$aART-2020-121738
000097440 041__ $$aeng
000097440 100__ $$aPérez-Gracia, J.
000097440 245__ $$aMisalignment and tilt effect on aspheric intraocular lens designs after a corneal refractive surgery
000097440 260__ $$c2020
000097440 5060_ $$aAccess copy available to the general public$$fUnrestricted
000097440 5203_ $$aPurpose: To numerically evaluate and compare the tolerance to misalignment and tilt of aspheric intraocular lenses (IOLs) designed for three eyes: with standard cornea and with simulated corneas after myopic and hyperopic laser ablation surgery.
Methods: Three aspheric IOLs of +20.00 diopter (D) with different spherical aberration (SA) (Z04) values have been designed using a theoretical model eye. Drastic changes on the theoretical eye anterior corneal asphericity have been performed to simulate myopic and hyperopic refractive surgeries. The effect of IOL misalignment and tilt on the image quality has been evaluated using a commercial optical software design for the three eye models. Image quality was assessed from the modulation transfer function (MTF), root mean square (RMS) values of defocus, astigmatism, coma and spherical aberration (Z04), and retinal images obtained from a visual simulator using an aleatory optotype of 0.00 LogMar visual acuity (VA).
Results: IOL misalignment and tilt reduced MTF values in general, and increased wavefront aberrations errors. Aberration-free IOLs maintained best the MTF values when misalignments were applied, together with good on-axis optical quality. IOLs with negative SA (Z04) correction decreased the MTF value under 0.43 for misalignments values higher than 0.50 mm with the three corneas. The effect of misalignment on RMS astigmatism and coma was correlated with the IOL SA (Z04) and with the three corneas.
Conclusions: This theoretical study shows that the largest degradation in image quality arises for the IOL with the highest amount of spherical aberration (Z04). Moreover, it has been found that the aspherical design has a more influential role in misalignment tolerance than in tilt tolerance.
000097440 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/Construyendo Europa desde Aragón$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/E24-17R$$9info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84047-R
000097440 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000097440 590__ $$a3.24$$b2020
000097440 591__ $$aMULTIDISCIPLINARY SCIENCES$$b26 / 73 = 0.356$$c2020$$dQ2$$eT2
000097440 592__ $$a0.99$$b2020
000097440 593__ $$aMultidisciplinary$$c2020$$dQ1
000097440 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000097440 700__ $$0(orcid)0000-0002-9068-7728$$aÁvila, F.J.$$uUniversidad de Zaragoza
000097440 700__ $$0(orcid)0000-0002-1124-0363$$aAres, J.$$uUniversidad de Zaragoza
000097440 700__ $$0(orcid)0000-0001-8431-0003$$aVallés, J.A.$$uUniversidad de Zaragoza
000097440 700__ $$0(orcid)0000-0002-3979-4528$$aRemón, L.$$uUniversidad de Zaragoza
000097440 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000097440 773__ $$g15, 12 (2020), e0243740 [17 pp]$$pPLoS One$$tPloS one$$x1932-6203
000097440 8564_ $$s678621$$uhttps://zaguan.unizar.es/record/97440/files/texto_completo.pdf$$yVersión publicada
000097440 8564_ $$s423118$$uhttps://zaguan.unizar.es/record/97440/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000097440 909CO $$ooai:zaguan.unizar.es:97440$$particulos$$pdriver
000097440 951__ $$a2021-09-02-10:25:55
000097440 980__ $$aARTICLE